Mpox virus mRNA-lipid nanoparticle vaccine candidates evoke antibody responses and drive protection against the Vaccinia virus challenge in mice

H Xia, YR He, XY Zhan, GF Zha - Antiviral Research, 2023 - Elsevier
In response to the human Mpox (hMPX) epidemic that began in 2022, there is an urgent
need for a monkeypox vaccine. Here, we have developed a series of mRNA-lipid …

Opto-microfluidic assisted synthesis of photo-protoporphyrin (pPP) conjugated to hollow gold-albumin hybrid nanoshells to enhance the efficiency of photodynamic …

A Imanparast, SAM Shaegh, N Attaran… - Photodiagnosis and …, 2023 - Elsevier
Abstract Introduction Protoporphyrin-IX (PpIX), a photosensitizer used in photodynamic
therapy, has limitations due to its hydrophobicity, rapid photobleaching, and low absorption …

Design and immunogenicity of SARS-coV-2 DNA vaccine encoding RBD-PVXCP fusion protein

D Dormeshkin, M Katsin, M Stegantseva… - Vaccines, 2023 - mdpi.com
The potential of immune-evasive mutation accumulation in the SARS-CoV-2 virus has led to
its rapid spread, causing over 600 million confirmed cases and more than 6.5 million …

Safety and immunogenicity of COReNAPCIN, a SARS-CoV-2 mRNA vaccine, as a fourth heterologous booster in healthy Iranian adults: A double-blind, randomized …

M Salehi, IA Darazam, A Nematollahi… - International …, 2024 - Elsevier
The recurrent COVID-19 infection, despite global vaccination, highlights the need for booster
doses. A heterologous booster has been suggested to enhance immunity and protection …

Novel synthesized ionizable lipid for LNP-mediated P2X7siRNA to inhibit migration and induce apoptosis of breast cancer cells

SH Kiaie, AR Zangi, M Sheibani, S Hemmati… - Purinergic …, 2024 - Springer
The development of ionizable lipid (IL) was necessary to enable the effective formulation of
small interfering RNA (siRNA) to inhibit P2X7 receptors (P2X7R), a key player in tumor …

Safety and immunogenicity of COReNAPCIN®, a SARS-CoV-2 mRNA vaccine; a randomized, double-blind, placebo-controlled phase 1 clinical trial

M Salehi, IA Darazam, A Nematollahi… - medRxiv, 2023 - medrxiv.org
The repeated COVID-19 outbreaks, despite global vaccination, highlights the need for
booster doses. Here, we present the outcomes, up until day 90 post vaccination, of a …

Produção de Antígeno Multiepítopo Sintético do SARS-CoV-2 em Sistema de Expressão Bacteriano

MATM Gama - 2022 - repositorio.ufpe.br
Atualmente, o processo de imunização da população mundial contra o SARS-CoV-2,
responsável pelo quadro pandêmico mais impactante para a saúde pública dos últimos …