A review of exosomal isolation methods: is size exclusion chromatography the best option?

K Sidhom, PO Obi, A Saleem - International journal of molecular sciences, 2020 - mdpi.com
Extracellular vesicles (EVs) are membranous vesicles secreted by both prokaryotic and
eukaryotic cells and play a vital role in intercellular communication. EVs are classified into …

Contribution of semen to early embryo development: fertilization and beyond

M Vallet-Buisan, R Mecca, C Jones… - Human …, 2023 - academic.oup.com
BACKGROUND It has long been thought that the factors affecting embryo and foetal
development were exclusively maternally derived; hence, if issues regarding fertility and …

Extracellular vesicles as therapeutic resources in the clinical environment

J Sanz-Ros, C Mas-Bargues, N Romero-García… - International journal of …, 2023 - mdpi.com
The native role of extracellular vesicles (EVs) in mediating the transfer of biomolecules
between cells has raised the possibility to use them as therapeutic vehicles. The …

[HTML][HTML] The female response to seminal fluid

JE Schjenken, SA Robertson - Physiological reviews, 2020 - journals.physiology.org
Seminal fluid is often assumed to have just one function in mammalian reproduction,
delivering sperm to fertilize oocytes. But seminal fluid also transmits signaling agents that …

Embryo implantation in the laboratory: an update on current techniques

S Ojosnegros, A Seriola, AL Godeau… - Human reproduction …, 2021 - academic.oup.com
BACKGROUND The embryo implantation process is crucial for the correct establishment
and progress of pregnancy. During implantation, the blastocyst trophectoderm cells attach to …

[HTML][HTML] Exosomes: New regulators of reproductive development

C Chen, Z Zhang, X Gu, X Sheng, L Xiao, X Wang - Materials Today Bio, 2023 - Elsevier
Exosomes are a subtype of extracellular vesicles (EVs) with a size range between 30 and
150​ nm, which can be released by the majority of cell types and circulate in body fluid …

Roles of male reproductive tract extracellular vesicles in reproduction

CT Tamessar, NA Trigg, B Nixon… - American Journal of …, 2021 - Wiley Online Library
Extracellular vesicles (EVs) are secreted cell‐derived membrane structures present in all
organisms across animal, bacterial, and plant phyla. These vesicles play important roles in …

Circulating exosome cargoes contain functionally diverse cancer biomarkers: from biogenesis and function to purification and potential translational utility

MI Mitchell, J Ma, CL Carter, O Loudig - Cancers, 2022 - mdpi.com
Simple Summary The indolent nature of some cancers makes early detection challenging,
as such significant effort is placed on identifying circulating cancer biomarkers using …

Protective roles of seminal plasma exosomes and microvesicles during human sperm cryopreservation

F Mahdavinezhad, MAS Gilani, R Gharaei… - Reproductive …, 2022 - Elsevier
Research question Do seminal plasma microvesicles and exosomes, as two subtypes of
extracellular vesicles, exert cryoprotective properties in sperm cryopreservation? Design …

Sperm modulate uterine immune parameters relevant to embryo implantation and reproductive success in mice

JE Schjenken, DJ Sharkey, ES Green, HY Chan… - Communications …, 2021 - nature.com
Seminal fluid factors modulate the female immune response at conception to facilitate
embryo implantation and reproductive success. Whether sperm affect this response has not …