Recent progress in non-photolithographic patterning of polymer thin films

M Qiu, W Du, S Zhou, P Cai, Y Luo, X Wang… - Progress in Polymer …, 2023 - Elsevier
Patterned polymer thin films are essential components in many devices and applications
owing to the multi-functionality, flexibility, lightweight and cost-efficiency. Unfortunately …

Advanced functional biomaterials for stem cell delivery in regenerative engineering and medicine

X Wang, N Rivera‐Bolanos, B Jiang… - Advanced Functional …, 2019 - Wiley Online Library
Stem cell–based therapies can potentially regenerate many types of tissues and organs,
thereby providing solutions to a variety of diseases and injuries. However, acute cell death …

A patch of detachable hybrid microneedle depot for localized delivery of mesenchymal stem cells in regeneration therapy

KJ Lee, Y Xue, J Lee, HJ Kim, Y Liu… - Advanced Functional …, 2020 - Wiley Online Library
Mesenchymal stem cells (MSCs) have been widely used for regenerative therapy. In most
current clinical applications, MSCs are delivered by injection but face significant issues with …

Micropattern-controlled chirality of focal adhesions regulates the cytoskeletal arrangement and gene transfection of mesenchymal stem cells

Y Wang, Y Yang, X Wang, T Yoshitomi, N Kawazoe… - Biomaterials, 2021 - Elsevier
Cell chirality has been demonstrated to be important for controlling cell functions. However,
it is not clear how the chirality of the extracellular microenvironment regulates cell adhesion …

The varied influences of cell adhesion and spreading on gene transfection of mesenchymal stem cells on a micropatterned substrate

Y Wang, Y Yang, X Wang, N Kawazoe, Y Yang… - Acta Biomaterialia, 2021 - Elsevier
Transmembrane transport of exogenous genes is widely investigated because of high
demand for gene therapy. Both gene carriers and cellular conditions can affect gene …

Influence of cell spreading area on the osteogenic commitment and phenotype maintenance of mesenchymal stem cells

Y Yang, X Wang, Y Wang, X Hu, N Kawazoe, Y Yang… - Scientific reports, 2019 - nature.com
Osteogenic differentiation and commitment of mesenchymal stem cells (MSCs) is a complex
process that is induced and regulated by various biological factors and biophysical cues …

Encapsulation of individual living cells with enzyme responsive polymer nanoshell

J Yang, Y Yang, N Kawazoe, G Chen - Biomaterials, 2019 - Elsevier
Cell delivery in cell therapy is typically challenged by the low cell survival rate and
immunological rejection during cells injection and circulation. Encapsulation of cells with …

Nano-sized graphene oxide coated nanopillars on microgroove polymer arrays that enhance skeletal muscle cell differentiation

HK Choi, CH Kim, SN Lee, TH Kim, BK Oh - Nano Convergence, 2021 - Springer
The degeneration or loss of skeletal muscles, which can be caused by traumatic injury or
disease, impacts most aspects of human activity. Among various techniques reported to …

Nano-imprinted anisotropic structural color graphene films for cardiomyocytes dynamic displaying

C Shao, J Chi, Z Chen, L Sun, L Shang, Y Zhao, F Ye - Materials Today, 2021 - Elsevier
Cellular mechanics plays an important role in physiological processes such as cell growth,
differentiation, apoptosis and gene expression. Herein, we present a nano-imprinted …

PLGA–collagen–ECM hybrid scaffolds functionalized with biomimetic extracellular matrices secreted by mesenchymal stem cells during stepwise osteogenesis-co …

Y Chen, K Lee, N Kawazoe, Y Yang… - Journal of Materials …, 2019 - pubs.rsc.org
A shift in osteogenesis toward adipogenesis of human bone marrow-derived mesenchymal
stem cells (hMSCs) is a crucial pathological factor in the progression of osteoporosis. The …