New insights into the evasion of host innate immunity by Mycobacterium tuberculosis

Q Chai, L Wang, CH Liu, B Ge - Cellular & molecular immunology, 2020 - nature.com
Mycobacterium tuberculosis (Mtb) is an extremely successful intracellular pathogen that
causes tuberculosis (TB), which remains the leading infectious cause of human death. The …

Nontuberculous mycobacteria, macrophages, and host innate immune response

M Shamaei, M Mirsaeidi - Infection and immunity, 2021 - Am Soc Microbiol
Although nontuberculous mycobacteria (NTM) are considered opportunistic infections,
incidence and prevalence of NTM infection are increasing worldwide becoming a major …

Virulence Mechanisms of Mycobacterium abscessus: Current Knowledge and Implications for Vaccine Design

KC Ferrell, MD Johansen, JA Triccas… - Frontiers in …, 2022 - frontiersin.org
Mycobacterium abscessus is a member of the non-tuberculous mycobacteria (NTM) group,
responsible for chronic infections in individuals with cystic fibrosis (CF) or those otherwise …

Tuberculosis diagnostics: overcoming ancient challenges with modern solutions

M MacGregor-Fairlie, S Wilkinson… - Emerging topics in …, 2020 - portlandpress.com
Rapid, sensitive, accurate and portable diagnostics are a mainstay of modern medicine.
Tuberculosis is a disease that has been with us since time immemorial and, despite the fact …

Virulence Factors of Mycobacterium tuberculosis as Modulators of Cell Death Mechanisms

LA Ramon-Luing, Y Palacios, A Ruiz… - Pathogens, 2023 - mdpi.com
Mycobacterium tuberculosis (Mtb) modulates diverse cell death pathways to escape the host
immune responses and favor its dissemination, a complex process of interest in …

Protective Efficacy of BCG Vaccine against Mycobacterium leprae and Non-Tuberculous Mycobacterial Infections

D Orujyan, W Narinyan, S Rangarajan, P Rangchaikul… - Vaccines, 2022 - mdpi.com
The genus mycobacterium includes several species that are known to cause infections in
humans. The microorganisms are classified into tuberculous and non-tuberculous based on …

MiR-144-3p is associated with pathological inflammation in patients infected with Mycobacteroides abscessus

HJ Kim, IS Kim, SG Lee, YJ Kim, P Silwal… - … & molecular medicine, 2021 - nature.com
Infection with rapidly growing nontuberculous mycobacteria is emerging as a global health
issue; however, key host factors remain elusive. Here, we investigated the characteristic …

Biotin-dependent cell envelope remodelling is required for Mycobacterium abscessus survival in lung infection

MR Sullivan, K McGowen, Q Liu, C Akusobi… - Nature …, 2023 - nature.com
Mycobacterium abscessus is an emerging pathogen causing lung infection predominantly in
patients with underlying structural abnormalities or lung disease and is resistant to most …

Autophagy and host defense in nontuberculous mycobacterial infection

P Silwal, IS Kim, EK Jo - Frontiers in immunology, 2021 - frontiersin.org
Autophagy is critically involved in host defense pathways through targeting and elimination
of numerous pathogens via autophagic machinery. Nontuberculous mycobacteria (NTMs) …

Manipulation and Exploitation Of Host Immune System by Pathogenic Mycobacterium Tuberculosis for its Advantage

MA Mir, B Mir, M Kumawat, M Alkhanani… - Future Microbiology, 2022 - Taylor & Francis
Mycobacterium tuberculosis (Mtb) can become a long-term infection by evading the host
immune response. Coevolution of Mtb with humans has resulted in its ability to hijack the …