Disease-suppressive soils—beyond food production: a critical review

S Jayaraman, AK Naorem, R Lal, RC Dalal… - Journal of Soil Science …, 2021 - Springer
In the pursuit of higher food production and economic growth and increasing population, we
have often jeopardized natural resources such as soil, water, vegetation, and biodiversity at …

Secondary metabolites of actinomycetes and their antibacterial, antifungal and antiviral properties

K Jakubiec-Krzesniak, A Rajnisz-Mateusiak… - Polish journal of …, 2018 - sciendo.com
The growing resistance of microorganisms towards antibiotics has become a serious global
problem. Therapeutics with novel chemical scaffolds and/or mechanisms of action are …

Concepts and methods to access novel antibiotics from actinomycetes

JJ Hug, CD Bader, M Remškar, K Cirnski, R Müller - Antibiotics, 2018 - mdpi.com
Actinomycetes have been proven to be an excellent source of secondary metabolites for
more than half a century. Exhibiting various bioactivities, they provide valuable approved …

The extremophilic actinobacteria: from microbes to medicine

MLY Hui, LTH Tan, V Letchumanan, YW He, CM Fang… - Antibiotics, 2021 - mdpi.com
Actinobacteria constitute prolific sources of novel and vital bioactive metabolites for
pharmaceutical utilization. In recent years, research has focused on exploring actinobacteria …

Anticancer drug discovery from microbial sources: The unique mangrove streptomycetes

JWF Law, LNS Law, V Letchumanan, LTH Tan… - Molecules, 2020 - mdpi.com
Worldwide cancer incidence and mortality have always been a concern to the community.
The cancer mortality rate has generally declined over the years; however, there is still an …

Mangrove rare actinobacteria: taxonomy, natural compound, and discovery of bioactivity

AS Azman, I Othman, SS Velu, KG Chan… - Frontiers in …, 2015 - frontiersin.org
Actinobacteria are one of the most important and efficient groups of natural metabolite
producers. The genus Streptomyces have been recognized as prolific producers of useful …

Presence of antioxidative agent, Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro- in newly isolated Streptomyces mangrovisoli sp. nov.

HL Ser, UD Palanisamy, WF Yin… - Frontiers in …, 2015 - frontiersin.org
A novel Streptomyces, strain MUSC 149T was isolated from mangrove soil. A polyphasic
approach was used to study the taxonomy of MUSC 149T, which shows a range of …

Diversity and antimicrobial activities of actinobacteria isolated from tropical mangrove sediments in Malaysia

LH Lee, N Zainal, AS Azman, SK Eng… - The scientific world …, 2014 - Wiley Online Library
The aim of this study was to isolate and identify Actinobacteria from Malaysia mangrove
forest and screen them for production of antimicrobial secondary metabolites. Eighty‐seven …

Streptomyces learnhanii sp. nov., unveiling a Mangrove-Derived Novel “Modern Actinobacteria” in Malaysia

JWF Law, V Letchumanan… - … In Microbes & …, 2023 - journals.hh-publisher.com
Streptomyces learnhanii sp. nov. MUM 203J T was isolated from Malaysia mangrove soil.
This Gram-positive bacterium produces pale greenish-yellow aerial and greyish-yellow …

Metabolic engineering to synthetic biology of secondary metabolites production

AN Yadav, D Kour, KL Rana, N Yadav, B Singh… - New and future …, 2019 - Elsevier
The microbial secondary metabolites have great importance for humans and agriculture.
They are widely used as active drug ingredients in medicine (eg, many antibiotics, antitumor …