B cell depletion therapies in autoimmune disease: advances and mechanistic insights
DSW Lee, OL Rojas, JL Gommerman - Nature reviews Drug discovery, 2021 - nature.com
In the past 15 years, B cells have been rediscovered to be not merely bystanders but rather
active participants in autoimmune aetiology. This has been fuelled in part by the clinical …
active participants in autoimmune aetiology. This has been fuelled in part by the clinical …
Immune mechanisms of hypertension
GR Drummond, A Vinh, TJ Guzik… - Nature Reviews …, 2019 - nature.com
Hypertension affects 30% of adults and is the leading risk factor for heart attack and stroke.
Traditionally, hypertension has been regarded as a disorder of two systems that are involved …
Traditionally, hypertension has been regarded as a disorder of two systems that are involved …
Hypertension: do inflammation and immunity hold the key to solving this epidemic?
Elevated cardiovascular risk including stroke, heart failure, and heart attack is present even
after normalization of blood pressure in patients with hypertension. Underlying immune cell …
after normalization of blood pressure in patients with hypertension. Underlying immune cell …
Immune and inflammatory mechanisms in hypertension
TJ Guzik, R Nosalski, P Maffia… - Nature Reviews …, 2024 - nature.com
Hypertension is a global health problem, with> 1.3 billion individuals with high blood
pressure worldwide. In this Review, we present an inflammatory paradigm for hypertension …
pressure worldwide. In this Review, we present an inflammatory paradigm for hypertension …
Vascular remodelling in cardiovascular diseases: hypertension, oxidation, and inflammation
J Totoń-Żurańska, TP Mikolajczyk, B Saju… - Clinical …, 2024 - portlandpress.com
Optimal vascular structure and function are essential for maintaining the physiological
functions of the cardiovascular system. Vascular remodelling involves changes in vessel …
functions of the cardiovascular system. Vascular remodelling involves changes in vessel …
Adaptive immunity in hypertension
TP Mikolajczyk, TJ Guzik - Current hypertension reports, 2019 - Springer
Abstract Purpose of Review In recent years, a vast body of evidence has accumulated
indicating the role of the immune system in the regulation of blood pressure and modulation …
indicating the role of the immune system in the regulation of blood pressure and modulation …
Immune mechanisms in arterial hypertension. Recent advances
UO Wenzel, H Ehmke, M Bode - Cell and Tissue Research, 2021 - Springer
Increasing evidence indicates that hypertension and hypertensive end-organ damage are
not only mediated by hemodynamic injury. Inflammation also plays an important role in the …
not only mediated by hemodynamic injury. Inflammation also plays an important role in the …
Peripheral immune cell composition is altered in women before and after a hypertension diagnosis
Background: The development and consequences of hypertension involve multiple
biological systems that may include changes in immune profiles. Whether hypertension is …
biological systems that may include changes in immune profiles. Whether hypertension is …
Development of a Fiber Bragg Grating-Based Force Sensor for Minimally Invasive Surgery–Case Study of Ex-Vivo Tissue Palpation
In this study, a 1-D distal force sensor design is proposed for minimally invasive surgery
(MIS) based on the fiber Bragg grating (FBG) sensing principle. The sensor is made with a …
(MIS) based on the fiber Bragg grating (FBG) sensing principle. The sensor is made with a …
Androgen-induced cardiovascular risk in polycystic ovary syndrome: the role of T lymphocytes
M Moulana - Life, 2023 - mdpi.com
An estimated 15–20% of reproductive-age women are affected by polycystic ovary
syndrome (PCOS). PCOS is associated with substantial metabolic and cardiovascular long …
syndrome (PCOS). PCOS is associated with substantial metabolic and cardiovascular long …