B cell depletion therapies in autoimmune disease: advances and mechanistic insights

DSW Lee, OL Rojas, JL Gommerman - Nature reviews Drug discovery, 2021 - nature.com
In the past 15 years, B cells have been rediscovered to be not merely bystanders but rather
active participants in autoimmune aetiology. This has been fuelled in part by the clinical …

Immune mechanisms of hypertension

GR Drummond, A Vinh, TJ Guzik… - Nature Reviews …, 2019 - nature.com
Hypertension affects 30% of adults and is the leading risk factor for heart attack and stroke.
Traditionally, hypertension has been regarded as a disorder of two systems that are involved …

Hypertension: do inflammation and immunity hold the key to solving this epidemic?

MS Madhur, F Elijovich, MR Alexander, A Pitzer… - Circulation …, 2021 - Am Heart Assoc
Elevated cardiovascular risk including stroke, heart failure, and heart attack is present even
after normalization of blood pressure in patients with hypertension. Underlying immune cell …

Immune and inflammatory mechanisms in hypertension

TJ Guzik, R Nosalski, P Maffia… - Nature Reviews …, 2024 - nature.com
Hypertension is a global health problem, with> 1.3 billion individuals with high blood
pressure worldwide. In this Review, we present an inflammatory paradigm for hypertension …

Vascular remodelling in cardiovascular diseases: hypertension, oxidation, and inflammation

J Totoń-Żurańska, TP Mikolajczyk, B Saju… - Clinical …, 2024 - portlandpress.com
Optimal vascular structure and function are essential for maintaining the physiological
functions of the cardiovascular system. Vascular remodelling involves changes in vessel …

Adaptive immunity in hypertension

TP Mikolajczyk, TJ Guzik - Current hypertension reports, 2019 - Springer
Abstract Purpose of Review In recent years, a vast body of evidence has accumulated
indicating the role of the immune system in the regulation of blood pressure and modulation …

Immune mechanisms in arterial hypertension. Recent advances

UO Wenzel, H Ehmke, M Bode - Cell and Tissue Research, 2021 - Springer
Increasing evidence indicates that hypertension and hypertensive end-organ damage are
not only mediated by hemodynamic injury. Inflammation also plays an important role in the …

Peripheral immune cell composition is altered in women before and after a hypertension diagnosis

JK Kresovich, Z Xu, KM O'Brien, CG Parks… - …, 2023 - Am Heart Assoc
Background: The development and consequences of hypertension involve multiple
biological systems that may include changes in immune profiles. Whether hypertension is …

Development of a Fiber Bragg Grating-Based Force Sensor for Minimally Invasive Surgery–Case Study of Ex-Vivo Tissue Palpation

L Gan, W Duan, TO Akinyemi, W Du… - IEEE Transactions …, 2021 - ieeexplore.ieee.org
In this study, a 1-D distal force sensor design is proposed for minimally invasive surgery
(MIS) based on the fiber Bragg grating (FBG) sensing principle. The sensor is made with a …

Androgen-induced cardiovascular risk in polycystic ovary syndrome: the role of T lymphocytes

M Moulana - Life, 2023 - mdpi.com
An estimated 15–20% of reproductive-age women are affected by polycystic ovary
syndrome (PCOS). PCOS is associated with substantial metabolic and cardiovascular long …