The human response to injury involves the coordinated interplay of a variety of physiologic
processes that result in a healed wound. In a highly reproducible manner, hemostasis is …

The leukotrienes and lipoxins are biologically active metabolites derived from arachidonic
acid. Their diverse and potent actions are associated with specific receptors. Recent …

The ability of intradermally injected leukotrienes C4 (LTC4), LTD4 and LTB4 to produce
inflammatory changes in human skin alone and in combination with prostaglandin E2 …

For a number of years it has been realized that there are important interactions between
arachidonic acid and its cyclooxygenase products and the anaphylactic mediator, slow …

1 Cells were dispersed from human foreskin using a mixture of collagenase and
hyaluronidase and separated into mast cell‐depleted (< 1%) or enriched (> 75%) …

In this issue of theArchives (page 548), Kragballe and Herlin describe a double-blind study
that clearly demonstrates that benoxaprofen is efficacious in the therapy of psoriasis. This …

Ten patients with psoriasis resistant to conventional topical treatment were given dietary
supplements of fish oil, providing approximately 12 g of eicosapentaenoic acid daily for a …

The leukotrienes (LTs) are a novel group of biologically active mediators derived from
arachidonic acid via lipoxygenase enzymes. LTB4 is a potent chemotactic agent for …

The leukotrienes are synthesized from essential fatty acids via a 5-lipoxygenase enzyme.
Most is known about the four-series leukotrienes derived from arachidonic acid. Leukotriene …

• Blister fluids from 39 previously untreated patients with pemphigus vulgaris (PV) and 28
patients with bullous pemphigoid (BP) were tested for the presence of inflammatory …