Microfluidic devices for drug delivery systems and drug screening

S Damiati, UB Kompella, SA Damiati, R Kodzius - Genes, 2018 - mdpi.com
Microfluidic devices present unique advantages for the development of efficient drug carrier
particles, cell-free protein synthesis systems, and rapid techniques for direct drug screening …

Microfluidics integrated biosensors: A leading technology towards lab-on-a-chip and sensing applications

G Luka, A Ahmadi, H Najjaran, E Alocilja, M DeRosa… - Sensors, 2015 - mdpi.com
A biosensor can be defined as a compact analytical device or unit incorporating a biological
or biologically derived sensitive recognition element immobilized on a physicochemical …

Three-dimensional manipulation of single cells using surface acoustic waves

F Guo, Z Mao, Y Chen, Z Xie, JP Lata… - Proceedings of the …, 2016 - National Acad Sciences
The ability of surface acoustic waves to trap and manipulate micrometer-scale particles and
biological cells has led to many applications involving “acoustic tweezers” in biology …

3D printing: an emerging tool for novel microfluidics and lab-on-a-chip applications

AA Yazdi, A Popma, W Wong, T Nguyen, Y Pan… - Microfluidics and …, 2016 - Springer
In the past few years, 3D printing technology has witnessed an explosive growth,
penetrating various aspects of our lives. Current best-in-class 3D printers can fabricate …

Biomimetic tissues on a chip for drug discovery

AM Ghaemmaghami, MJ Hancock, H Harrington… - Drug discovery today, 2012 - Elsevier
Developing biologically relevant models of human tissues and organs is an important
enabling step for disease modeling and drug discovery. Recent advances in tissue …

Organs-on-chips: breaking the in vitro impasse

AD Van Der Meer, A Van Den Berg - Integrative Biology, 2012 - academic.oup.com
In vitro models of biological tissues are indispensable tools for unraveling human physiology
and pathogenesis. They usually consist of a single layer of a single cell type, which makes …

Axon diodes for the reconstruction of oriented neuronal networks in microfluidic chambers

JM Peyrin, B Deleglise, L Saias, M Vignes, P Gougis… - Lab on a Chip, 2011 - pubs.rsc.org
Various experimental models are used to study brain development and degeneration. They
range from whole animal models, which preserve anatomical structures but strongly limit …

Oscillating bubbles: a versatile tool for lab on a chip applications

A Hashmi, G Yu, M Reilly-Collette, G Heiman, J Xu - Lab on a Chip, 2012 - pubs.rsc.org
With the fast development of acoustic and multiphase microfluidics in recent years,
oscillating bubbles have drawn more-and-more attention due to their great potential in …

Microfluidics for manipulating cells

X Mu, W Zheng, J Sun, W Zhang, X Jiang - small, 2013 - Wiley Online Library
Microfluidics, a toolbox comprising methods for precise manipulation of fluids at small length
scales (micrometers to millimeters), has become useful for manipulating cells. Its uses range …

Challenges in the development of organic and hybrid molecular systems

VP Ananikov, KI Galkin, MP Egorov… - Mendeleev …, 2016 - Elsevier
The rapid development of organic chemistry and catalysis has provided outstanding
chemical tools to build complex molecular architectures that were never possible before. In …