Structure, biophysics, and circuit function of a “giant” cortical presynaptic terminal
The hippocampal mossy fiber synapse, formed between axons of dentate gyrus granule
cells and dendrites of CA3 pyramidal neurons, is a key synapse in the trisynaptic circuitry of …
cells and dendrites of CA3 pyramidal neurons, is a key synapse in the trisynaptic circuitry of …
Entorhinal cortex vulnerability to human APP expression promotes hyperexcitability and tau pathology
Preventative treatment for Alzheimer's Disease (AD) is dire, yet mechanisms underlying
early regional vulnerability remain unknown. In AD, one of the earliest pathophysiological …
early regional vulnerability remain unknown. In AD, one of the earliest pathophysiological …
Human hippocampal CA3 uses specific functional connectivity rules for efficient associative memory
JF Watson, V Vargas-Barroso, RJ Morse-Mora… - bioRxiv, 2024 - biorxiv.org
The human brain has remarkable computational power. It generates sophisticated
behavioral sequences, stores engrams over an individual's lifetime, and produces higher …
behavioral sequences, stores engrams over an individual's lifetime, and produces higher …
A non-Hebbian code for episodic memory
R Pang, S Recanatesi - bioRxiv, 2024 - biorxiv.org
Hebbian plasticity has long dominated neurobiological models of memory formation. Yet
plasticity rules operating on one-shot episodic memory timescales rarely depend on both …
plasticity rules operating on one-shot episodic memory timescales rarely depend on both …
Investigation of Presynaptic Plasticity Mechanisms at the Hippocampal Mossy Fiber Bouton
F Brüntgens - 2024 - refubium.fu-berlin.de
Hippokampale Moosfaser Boutons sind große, plastische Synapsen, die Körnerzellen aus
dem Gyrus dentatus mit CA3 Pyramidenzellen verbinden. Sie spielen eine substanzielle …
dem Gyrus dentatus mit CA3 Pyramidenzellen verbinden. Sie spielen eine substanzielle …