Bone stress injuries, including stress fractures, are overuse injuries that lead to substantial
morbidity in active individuals. These injuries occur when excessive repetitive loads are …

Bone tissue engineering (BTE) is a topic of interest for the last decade, and advances in
materials, processing techniques, and the understanding of bone healing pathways have …

The integration of structure and function for tissue engineering scaffolds is of great
importance in mimicking native bone tissue. However, the complexity of hierarchical …

Bone remodeling is tightly regulated by a cross-talk between bone-forming osteoblasts and
bone-resorbing osteoclasts. Osteoblasts and osteoclasts communicate with each other to …

Context Denosumab discontinuation is characterized by an increase in bone turnover
overriding pretreatment status, a rapid bone loss in the majority and multiple vertebral …

Bone has a remarkable endogenous regenerative capacity that enables scarless healing
and restoration of its prior mechanical function, even under challenging conditions such as …

Skeletal disorders are among the leading debilitating factors affecting millions of people
worldwide. The use of stem cells for tissue repair has raised many promises in various …

The development, maintenance of healthy bone and regeneration of injured tissue in the
human body comprise a set of intricate and finely coordinated processes. However, an …

Bone remodeling is the continual process to renew the adult skeleton through the sequential
action of osteoblasts and osteoclasts. Nuclear factor RANK, an osteoclast receptor, and its …

An expanding body of research asserts that the gut microbiota has a role in bone
metabolism and the pathogenesis of osteoporosis. This review considers the human gut …