Vitamin D status and SARS-CoV-2 infection and COVID-19 clinical outcomes

I Chiodini, D Gatti, D Soranna, D Merlotti… - Frontiers in Public …, 2021 - frontiersin.org
Background: Several studies suggest an association between serum 25-hydroxyvitamin D
(25OHD) and the outcomes of Severe Acute Respiratory Syndrome Corona-Virus-2 (SARS …

[HTML][HTML] Vitamin D and immune function

B Prietl, G Treiber, TR Pieber, K Amrein - Nutrients, 2013 - mdpi.com
Vitamin D metabolizing enzymes and vitamin D receptors are present in many cell types
including various immune cells such as antigen-presenting-cells, T cells, B cells and …

Vitamin D and immune regulation: antibacterial, antiviral, anti-inflammatory

EL Bishop, A Ismailova, S Dimeloe… - Journal of Bone and …, 2021 - academic.oup.com
Regulation of immune function continues to be one of the most well recognized extraskeletal
actions of vitamin D. This stemmed initially from the discovery that antigen presenting cells …

Vitamin D: effect on haematopoiesis and immune system and clinical applications

M Medrano, E Carrillo-Cruz, I Montero… - International journal of …, 2018 - mdpi.com
Vitamin D is a steroid-like hormone which acts by binding to vitamin D receptor (VDR). It
plays a main role in the calcium homeostasis and metabolism. In addition, vitamin D display …

Cellular metabolism and macrophage functional polarization

L Zhu, Q Zhao, T Yang, W Ding… - International reviews of …, 2015 - Taylor & Francis
Macrophages are a functionally heterogeneous cell population that is mainly shaped by a
variety of microenvironmental stimuli. Interferon γ (IFN-γ), interleukin-1β (IL-1β), and …

An update on vitamin D and human immunity

M Hewison - Clinical endocrinology, 2012 - Wiley Online Library
In the last 5 years, there has been a remarkable change in our understanding of the health
benefits of vitamin D. The classical actions of vitamin D as a determinant of mineral …

Impact of vitamin D on immune function: lessons learned from genome-wide analysis

RF Chun, PT Liu, RL Modlin, JS Adams… - Frontiers in …, 2014 - frontiersin.org
Immunomodulatory responses to the active form of vitamin D (1, 25-dihydroxyvitamin D, 1,
25D) have been recognized for many years, but it is only in the last 5 years that the potential …

[HTML][HTML] Nutrition, immunosenescence, and infectious disease: an overview of the scientific evidence on micronutrients and on modulation of the gut microbiota

PC Calder, EF Ortega, SN Meydani, Y Adkins… - Advances in …, 2022 - Elsevier
The immune system is key to host defense against pathogenic organisms. Aging is
associated with changes in the immune system, with a decline in protective components …

Immune modulatory effects of vitamin D on viral infections

M Siddiqui, JS Manansala, HA Abdulrahman… - Nutrients, 2020 - mdpi.com
Viral infections have been a cause of mortality for several centuries and continue to
endanger the lives of many, specifically of the younger population. Vitamin D has long been …

Combating bacterial infections with host defense peptides: shifting focus from bacteria to host immunity

N Gao, J Wang, C Fang, P Bai, Y Sun, W Wu… - Drug Resistance …, 2024 - Elsevier
The increasing prevalence of multidrug-resistant bacterial infections necessitates the
exploration of novel paradigms for anti-infective therapy. Antimicrobial peptides (AMPs), also …