Gastric cancer: epidemiology, risk factors, classification, genomic characteristics and treatment strategies

J Machlowska, J Baj, M Sitarz, R Maciejewski… - International journal of …, 2020 - mdpi.com
Gastric cancer (GC) is one of the most common malignancies worldwide and it is the fourth
leading cause of cancer-related death. GC is a multifactorial disease, where both …

Helicobacter pylori Virulence Factors—Mechanisms of Bacterial Pathogenicity in the Gastric Microenvironment

J Baj, A Forma, M Sitarz, P Portincasa, G Garruti… - Cells, 2020 - mdpi.com
Gastric cancer constitutes one of the most prevalent malignancies in both sexes; it is
currently the fourth major cause of cancer-related deaths worldwide. The pathogenesis of …

Tumor-associated macrophages and inflammatory microenvironment in gastric cancer: novel translational implications

K Rihawi, AD Ricci, A Rizzo, S Brocchi… - International Journal of …, 2021 - mdpi.com
Gastric cancer (GC) represents the fifth most frequently diagnosed cancer worldwide, with a
poor prognosis in patients with advanced disease despite many improvements in systemic …

Gastric cancer: advances in carcinogenesis research and new therapeutic strategies

L Seeneevassen, E Bessède, F Mégraud… - International journal of …, 2021 - mdpi.com
Gastric cancer's bad incidence, prognosis, cellular and molecular heterogeneity amongst
others make this disease a major health issue worldwide. Understanding this affliction is a …

Mechanisms of the Epithelial–Mesenchymal Transition and Tumor Microenvironment in Helicobacter pylori-Induced Gastric Cancer

J Baj, I Korona-Głowniak, A Forma, A Maani, E Sitarz… - Cells, 2020 - mdpi.com
Helicobacter pylori (H. pylori) is one of the most common human pathogens, affecting half of
the world's population. Approximately 20% of the infected patients develop gastric ulcers or …

Exploring the crosstalk between inflammation and epithelial‐mesenchymal transition in cancer

I Chattopadhyay, R Ambati… - Mediators of …, 2021 - Wiley Online Library
Tumor cells undergo invasion and metastasis through epithelial‐to‐mesenchymal cell
transition (EMT) by activation of alterations in extracellular matrix (ECM) protein‐encoding …

STAT3 pathway in gastric cancer: signaling, therapeutic targeting and future prospects

M Ashrafizadeh, A Zarrabi, S Orouei, V Zarrin… - Biology, 2020 - mdpi.com
Molecular signaling pathways play a significant role in the regulation of biological
mechanisms, and their abnormal expression can provide the conditions for cancer …

Helicobacter pylori Infection and Extragastric Diseases—A Focus on the Central Nervous System

J Baj, A Forma, W Flieger, I Morawska, A Michalski… - Cells, 2021 - mdpi.com
Helicobacter pylori (H. pylori) is most known to cause a wide spectrum of gastrointestinal
impairments; however, an increasing number of studies indicates that H. pylori infection …

Cancer stem cells and the tumor microenvironment in gastric cancer

Y Yang, WJ Meng, ZQ Wang - Frontiers in Oncology, 2022 - frontiersin.org
Gastric cancer (GC) remains one of the leading causes of cancer-related death worldwide.
Cancer stem cells (CSCs) might be responsible for tumor initiation, relapse, metastasis and …

Overview on the role of E-cadherin in gastric cancer: dysregulation and clinical implications

H Zhao, H Hu, B Chen, W Xu, J Zhao… - Frontiers in Molecular …, 2021 - frontiersin.org
Gastric cancer is the fifth most common cancer and the third most common cause of cancer
death all over the world. E-cadherin encoded by human CDH1 gene plays important roles in …