The epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant, extensively drug-resistant, and incurable tuberculosis
Global tuberculosis incidence has declined marginally over the past decade, and
tuberculosis remains out of control in several parts of the world including Africa and Asia …
tuberculosis remains out of control in several parts of the world including Africa and Asia …
[HTML][HTML] Evaluation of Genetic Mutations Associated with Mycobacterium tuberculosis Resistance to Amikacin, Kanamycin and Capreomycin: A Systematic Review
Background Rapid molecular diagnostics for detecting multidrug-resistant and extensively
drug-resistant tuberculosis (M/XDR-TB) primarily identify mutations in Mycobacterium …
drug-resistant tuberculosis (M/XDR-TB) primarily identify mutations in Mycobacterium …
A systematic review of gyrase mutations associated with fluoroquinolone-resistant Mycobacterium tuberculosis and a proposed gyrase numbering system
F Maruri, TR Sterling, AW Kaiga… - Journal of …, 2012 - academic.oup.com
Fluoroquinolone resistance in Mycobacterium tuberculosis has become increasingly
important. A review of mutations in DNA gyrase, the fluoroquinolone target, is needed to …
important. A review of mutations in DNA gyrase, the fluoroquinolone target, is needed to …
[HTML][HTML] Frequency and Geographic Distribution of gyrA and gyrB Mutations Associated with Fluoroquinolone Resistance in Clinical Mycobacterium Tuberculosis …
E Avalos, D Catanzaro, A Catanzaro, T Ganiats… - PloS one, 2015 - journals.plos.org
Background The detection of mutations in the gyrA and gyrB genes in the Mycobacterium
tuberculosis genome that have been demonstrated to confer phenotypic resistance to …
tuberculosis genome that have been demonstrated to confer phenotypic resistance to …
Drug resistance mechanisms and novel drug targets for tuberculosis therapy
Drug-resistant tuberculosis (TB) poses a significant challenge to the successful treatment
and control of TB worldwide. Resistance to anti-TB drugs has existed since the beginning of …
and control of TB worldwide. Resistance to anti-TB drugs has existed since the beginning of …
Insights into the processes that drive the evolution of drug resistance in Mycobacterium tuberculosis
QH Nguyen, L Contamin, TVA Nguyen… - Evolutionary …, 2018 - Wiley Online Library
At present, the successful transmission of drug‐resistant Mycobacterium tuberculosis,
including multidrug‐resistant (MDR) and extensively drug‐resistant (XDR) strains, in human …
including multidrug‐resistant (MDR) and extensively drug‐resistant (XDR) strains, in human …
Epidemiology of drug-resistant tuberculosis
As we move into the era of the Sustainable Development Goals (SDGs), the World Health
Organization (WHO) has developed the End TB strategy 2016–2035 with a goal to end the …
Organization (WHO) has developed the End TB strategy 2016–2035 with a goal to end the …
[HTML][HTML] Molecular characterization of amikacin, kanamycin and capreomycin resistance in M/XDR-TB strains isolated in Thailand
A Sowajassatakul, T Prammananan, A Chaiprasert… - BMC microbiology, 2014 - Springer
Background The emergence of multidrug-resistant tuberculosis (MDR-TB) and extensively
drug-resistant tuberculosis (XDR-TB) makes the treatment and control of tuberculosis …
drug-resistant tuberculosis (XDR-TB) makes the treatment and control of tuberculosis …
[HTML][HTML] Spontaneous emergence of multiple drug resistance in tuberculosis before and during therapy
The emergence of drug resistance in M. tuberculosis undermines the efficacy of tuberculosis
(TB) treatment in individuals and of TB control programs in populations. Multiple drug …
(TB) treatment in individuals and of TB control programs in populations. Multiple drug …
[HTML][HTML] Unraveling Mycobacterium tuberculosis genomic diversity and evolution in Lisbon, Portugal, a highly drug resistant setting
Background Multidrug-(MDR) and extensively drug resistant (XDR) tuberculosis (TB)
presents a challenge to disease control and elimination goals. In Lisbon, Portugal, specific …
presents a challenge to disease control and elimination goals. In Lisbon, Portugal, specific …