Posttranscriptional gene regulation includes mRNA transport, localization, translation, and
regulation of mRNA stability. CPEB (c ytoplasmic p olyadenylation e lement b inding) family …

How long-lived memories withstand molecular turnover is a fundamental question.
Aggregates of a prion-like RNA-binding protein, cytoplasmic polyadenylation element …

Spermatid elongation is a crucial event in the late stage of spermatogenesis in the
Drosophila testis, eventually leading to the formation of mature sperm after meiosis. During …

During oocyte maturation and early embryogenesis, changes in mRNA poly (A)-tail lengths
strongly influence translation, but how these tail-length changes are orchestrated has been …

Tissue-specific mRNA stability is important for cell fate and physiology, but the mechanisms
involved are not fully understood. We found that zygotic mRNA stability in Drosophila …

Background Vertebrate CPEB proteins bind mRNAs at cytoplasmic polyadenylation
elements (CPEs) in their 3′ UTRs, leading to cytoplasmic changes in their poly (A) tail …

Skeletal muscle stem cells, also called Satellite Cells (SCs), are actively maintained in
quiescence but can activate quickly upon extrinsic stimuli. However, the mechanisms of how …

Many insights into the molecular mechanisms underlying learning and memory have been
elucidated through the use of simple behavioral assays in model organisms such as the fruit …

Centrosomes are multifunctional organelles tasked with organizing the microtubule
cytoskeleton required for genome stability, intracellular trafficking, and ciliogenesis …

Transition through cell cycle phases requires temporal and spatial regulation of gene
expression to ensure accurate chromosome duplication and segregation. This regulation …