Issues in long-term protein delivery using biodegradable microparticles

M Ye, S Kim, K Park - Journal of Controlled Release, 2010 - Elsevier
Recently, a variety of bioactive protein drugs have been available in large quantities as a
result of advances in biotechnology. Such availability has prompted development of long …

Ligand binding strategies of human serum albumin: how can the cargo be utilized?

A Varshney, P Sen, E Ahmad, M Rehan… - Chirality: The …, 2010 - Wiley Online Library
Human serum albumin (HSA), being the most abundant carrier protein in blood and a
modern day clinical tool for drug delivery, attracts high attention among biologists. Hence, its …

Preparation and characterization of biodegradable paclitaxel loaded alginate microparticles for pulmonary delivery

S Alipour, H Montaseri, M Tafaghodi - Colloids and Surfaces B …, 2010 - Elsevier
In primary or metastatic lung cancer, administration of chemotherapeutic agents via
inhalation could increase exposure of lung tumor to the drug, while minimizing systemic side …

Exemestane loaded alginate nanoparticles for cancer treatment: formulation and in vitro evaluation

JJ Jayapal, S Dhanaraj - International journal of biological macromolecules, 2017 - Elsevier
Alginate, a biopolymer is most useful for anticancer drug delivery, because of it is
biocompatible, nontoxic, biodegradable and exploiting ligand-receptor interaction. Breast …

Alginate graft copolymers and alginate–co-excipient physical mixture in oral drug delivery

TW Wong - Journal of Pharmacy and Pharmacology, 2011 - academic.oup.com
Objectives Use of alginate graft copolymers in oral drug delivery reduces dosage form
manufacture complexity with reference to mixing or coating processes. It is deemed to give …

Fecal microbiota transplantation: a review on current formulations in Clostridioides difficile infection and future outlooks

A Rakotonirina, T Galperine… - Expert Opinion on …, 2022 - Taylor & Francis
Introduction The role of the gut microbiota in health and the pathogenesis of several
diseases has been highlighted in recent years. Even though the precise mechanisms …

Airbrush encapsulation of Lactobacillus rhamnosus GG in dry microbeads of alginate coated with regular buttermilk proteins

AM Hugues-Ayala, JA Sarabia-Sainz, H González-Rios… - LWT, 2020 - Elsevier
Lactobacillus rhamnosus GG (L. rhamnosus GG) loaded calcium alginate microbeads were
prepared via an airbrush system and subsequently coated with regular butter milk proteins …

Incorporation of lipid nanoparticles into calcium alginate beads and characterization of the encapsulated particles by differential scanning calorimetry

B Strasdat, H Bunjes - Food Hydrocolloids, 2013 - Elsevier
The aim of this study was to encapsulate lipid nanoparticle dispersions into calcium alginate
microbeads and to investigate the feasibility of this incorporation as well as the stability of …

Serum albumin-alginate microparticles prepared by transacylation: Relationship between physicochemical, structural and functional properties

I Hadef, B Rogé, F Edwards-Lévy - Biomacromolecules, 2015 - ACS Publications
Our laboratory develops a method of microencapsulation using a transacylation reaction in a
water-in-oil (W/O) emulsion. The method is based on the creation of amide bonds between …

Methods for the functionalisation of nanoparticles: new insights and perspectives

T Perrier, P Saulnier, JP Benoît - Chemistry–A European …, 2010 - Wiley Online Library
In the field of nanometre‐sized drug‐delivery systems, a wide range of colloidal systems
have been created in recent decades. All of the systems have a similar global structure, that …