Carbohydrates are central players in a number of important biological processes including
cell signaling, cell adhesion, and the regulation of biochemical pathways. Unlike nucleic …

Glycosaminoglycans (GAGs) are heterogeneous, negatively charged, macromolecules that
are found in animal tissues. Based on the form of component sugar, GAGs have been …

Cells run on carbohydrates. Glycans, sequences of carbohydrates conjugated to proteins
and lipids, are arguably the most abundant and structurally diverse class of molecules in …

Proteoglycans (PGs) are among the most structurally complex biomacromolecules in nature.
They are present in all animal cells and frequently exert their critical biological functions …

Glycosaminoglycans (GAGs) are heterogeneous acidic polysaccharides involved in a range
of biological functions. They have a significant influence on the regulation of cellular …

Glycosaminoglycans (GAGs) are a class of biologically important molecules, and their
structural analysis is the target of considerable research effort. Advances in tandem mass …

The structural characterization of sulfated glycosaminoglycan (GAG) carbohydrates remains
an important target for analytical chemists attributable to challenges introduced by the …

Hydrophilic metabolites play important roles in cellular energy metabolism, signal
transduction, immunity. However, there are challenges in both identification and …

Structural characterization of sulfated glycosaminoglycans (GAGs) by mass spectrometry
has long been a formidable analytical challenge owing to their high structural variability and …

Urinary glycosaminoglycans (GAGs) can reflect the health condition of a human being, and
the GAGs composition can be directly related to various diseases. In order to effectively …