The quality of the social environment can have profound influences on the development and
activity of neural systems with implications for numerous behavioral and physiological …

Schizophrenia is a major psychotic disorder with multifactorial etiology that includes
interactions between genetic vulnerability and environmental risk factors. In addition …

Social hierarchies are ubiquitous features of virtually all animal groups. The varying social
ranks of members within these groups have profound effects on both physical and emotional …

Chronic stress, in particular chronic psychosocial stress, is a risk factor in the aetiology of
various psychopathologies including anxiety-and depression-related disorders. Therefore …

Animal models of human diseases are in widespread use for biomedical research. Mouse
models with a mutation in a single gene or multiple genes are excellent research tools for …

Chronic or repeated stressor exposure can induce a number of maladaptive behavioral and
physiological consequences and among limbic structures, the bed nucleus of the stria …

The corticotropin-releasing factor (CRF) system plays a key role in a diversity of behaviors
accompanying stress, anxiety and depression. There is also substantial research on …

The lateral division of the bed nucleus of the stria terminalis (BNST), which forms part of the
circuitry regulating fear and anxiety, contains a large number of neurons expressing …

The bed nucleus of the stria terminalis (BNST) is a forebrain region highly responsive to
stress that expresses corticotropin-releasing hormone (CRH) and is implicated in mood …

Appropriate interactions between serotonin (5-HT) and stress pathways are critical for
maintaining homeostasis. Dysregulation of hypothalamic-pituitary-adrenal (HPA) stress axis …