Oxidative stress in human pathology and aging: molecular mechanisms and perspectives

YA Hajam, R Rani, SY Ganie, TA Sheikh, D Javaid… - Cells, 2022 - mdpi.com
Reactive oxygen and nitrogen species (RONS) are generated through various endogenous
and exogenous processes; however, they are neutralized by enzymatic and non-enzymatic …

Molecular mechanisms linking oxidative stress and diabetes mellitus

H Yaribeygi, T Sathyapalan, SL Atkin… - … medicine and cellular …, 2020 - Wiley Online Library
Type 2 diabetes mellitus (T2DM) is the most prevalent metabolic disorder characterized by
chronic hyperglycemia and an inadequate response to circulatory insulin by peripheral …

Role of polyphenols in combating Type 2 Diabetes and insulin resistance

M Shahwan, F Alhumaydhi, GM Ashraf… - International journal of …, 2022 - Elsevier
Compromised carbohydrate metabolism leading to hyperglycemia is the primary metabolic
disorder of non-insulin-dependent diabetes mellitus. Reformed digestion and altered …

Cardiovascular risk and obesity

C Cercato, FA Fonseca - Diabetology & metabolic syndrome, 2019 - Springer
Background This is an overview of the mechanisms of obesity and its relation to
cardiovascular risks, describing the available treatment options to manage this condition …

Molecular mechanisms of ROS production and oxidative stress in diabetes

P Newsholme, VF Cruzat, KN Keane… - Biochemical …, 2016 - portlandpress.com
Oxidative stress and chronic inflammation are known to be associated with the development
of metabolic diseases, including diabetes. Oxidative stress, an imbalance between oxidative …

Resveratrol in treating diabetes and its cardiovascular complications: a review of its mechanisms of action

M Su, W Zhao, S Xu, J Weng - Antioxidants, 2022 - mdpi.com
Diabetes mellitus (DM) is one of the most prevalent chronic diseases worldwide. High
morbidity and mortality caused by DM are closely linked to its complications in multiple …

Role of oxidative stress in diabetic cardiomyopathy

B De Geest, M Mishra - Antioxidants, 2022 - mdpi.com
Type 2 diabetes is a redox disease. Oxidative stress and chronic inflammation induce a
switch of metabolic homeostatic set points, leading to glucose intolerance. Several diabetes …

The role of oxidative stress and hypoxia in pancreatic beta-cell dysfunction in diabetes mellitus

PA Gerber, GA Rutter - Antioxidants & redox signaling, 2017 - liebertpub.com
Significance: Metabolic syndrome is a frequent precursor of type 2 diabetes mellitus (T2D), a
disease that currently affects∼ 8% of the adult population worldwide. Pancreatic beta-cell …

Priming of the neutrophil respiratory burst: role in host defense and inflammation

J El‐Benna, M Hurtado‐Nedelec… - Immunological …, 2016 - Wiley Online Library
Neutrophils are the major circulating white blood cells in humans. They play an essential
role in host defense against pathogens. In healthy individuals, circulating neutrophils are in …

Polyphenols and glycemic control

Y Kim, JB Keogh, PM Clifton - Nutrients, 2016 - mdpi.com
Growing evidence from animal studies supports the anti-diabetic properties of some dietary
polyphenols, suggesting that dietary polyphenols could be one dietary therapy for the …