Outer hair cells and electromotility

J Ashmore - Cold Spring Harbor perspectives in …, 2019 - perspectivesinmedicine.cshlp.org
Outer hair cells (OHCs) of the mammalian cochlea behave like actuators: they feed energy
into the cochlear partition and determine the overall mechanics of hearing. They do this by …

Multiscale modeling of mechanotransduction in the utricle

JH Nam, JW Grant, MH Rowe… - Journal of …, 2019 - journals.physiology.org
We review recent progress in using numerical models to relate utricular hair bundle and
otoconial membrane (OM) structure to the functional requirements imposed by natural …

Dimensions of a living cochlear hair bundle

KK Miller, P Atkinson, KR Mendoza… - Frontiers in Cell and …, 2021 - frontiersin.org
The hair bundle is the mechanosensory organelle of hair cells that detects mechanical
stimuli caused by sounds, head motions, and fluid flows. Each hair bundle is an assembly of …

Phase locking of auditory-nerve fibers reveals stereotyped distortions and an exponential transfer function with a level-dependent slope

AJ Peterson, P Heil - Journal of Neuroscience, 2019 - Soc Neuroscience
Phase locking of auditory-nerve-fiber (ANF) responses to the fine structure of acoustic stimuli
is a hallmark of the auditory system's temporal precision and is important for many aspects of …

Coupling between the stereocilia of rat sensory inner-hair-cell hair bundles is weak, shaping their sensitivity to stimulation

AL Scharr, DÓ Maoiléidigh, AJ Ricci - Journal of Neuroscience, 2023 - Soc Neuroscience
The hair bundle is the universal mechanosensory organelle of auditory, vestibular, and
lateral-line systems. A bundle comprises mechanically coupled stereocilia, whose …

The functional contributions of links in mammalian cochlear hair bundles

Z Zhu, W Reid, DÓ Maoiléidigh - AIP Conference Proceedings, 2024 - pubs.aip.org
In the mammalian cochlea, hair bundles of the sensory outer and inner hair cells detect
mechanical signals. A hair bundle comprises a set of rod-like stereocilia that pivot around …

Developing active artificial hair cell sensors inspired by the cochlear amplifier

S Davaria - 2021 - vtechworks.lib.vt.edu
The mammalian cochlea has been the inspiration to develope contemporary cochlear
implants and active dynamic sensors that operate in the sensor's resonance region and …

The neuroscience of hearing or how to do a hard job with soft components

J Ashmore - Brain and Neuroscience Advances, 2018 - journals.sagepub.com
The inner ear is a small and relatively inaccessible structure. The use of multiple biophysical
recording techniques from the late 1970s onwards, combined with molecular genetics to …