The biological olfactory system is the sensory system responsible for the detection of the
chemical composition of the environment. Several attempts to mimic biological olfactory …

This review is the sequel to the 2000 report on the recent advances in the chemistry of
odorants and it summarizes the developments in fragrance chemistry over the past 20 years …

Eukaryotic cells use G-protein coupled receptors to sense diverse signals, ranging from
chemical compounds to light. Here, we exploit the remarkable sensing capacity of G-protein …

Systems that allow researchers to precisely control the expression of genes are fundamental
to biological research, biotechnology, and synthetic biology. However, few inducible gene …

G protein-coupled receptors (GPCRs) detect compounds on the cell surface and are the
starting point of a number of medically relevant signaling cascades. Indeed, over 30% of …

Prompted by the ground-breaking discovery of the rodent odorant receptor (OR) gene family
within the olfactory epithelium nearly 30 years ago, followed by that of OR genes in cells of …

Musk was originally identified in male musk deer and other mammals to mark territories and
attract females. In humans, musk compounds are widely used in perfumes and consumer …

ABSTRACT G protein-coupled receptors (GPCRs) comprise the largest class of membrane
proteins in the human genome, with a common denominator of seven-transmembrane …

G protein–coupled receptors (GPCRs) are a superfamily of transmembrane signal
transducers that facilitate the flow of chemical signals across membranes. GPCRs are a …

Mammalian sense of smell is triggered by interaction between odorant molecules and a
class of proteins, called olfactory receptors (ORs). These receptors, expressed at the surface …