Blood–brain barrier (BBB) strictly controls matter exchange between blood and brain, and
severely limits brain penetration of systemically administered drugs, resulting in ineffective …

Platelets exhibit distinct surface moieties responsible for modulating their adhesion to
various disease‐relevant substrates involving vascular damage, immune evasion, and …

Drug delivery for tumor theranostics involves the extensive use of the enhanced permeability
and retention (EPR) effect. Previously, various types of nanomedicines have been …

Early diagnosis and treatment of acute ischemic stroke poses a significant challenge due to
its suddenness and short therapeutic time window. Human endogenous cells derived …

Ultrasound (US) medical technology is widely used due to its advantages of safety, speed,
and low cost. With the rapid development of biomedical nanotechnology …

Rapid cut‐off of blood supply in diseases involving thrombosis is a major cause of morbidity
and mortality worldwide. However, the current thrombolysis strategies offer limited results …

Ischemic stroke caused by a thrombus clog and ischemia is one of the most lethal and
disabling cerebrovascular diseases. A sequentially targeted delivery system is highly …

Central nervous system (CNS) disorders, including brain tumor, ischemic stroke, Alzheimer's
disease, and Parkinson's disease, threaten human health. And the existence of the blood …

Ischemic stroke leads to high disability and mortality. The limited delivery efficiency of most
therapeutic substances is a major challenge for effective treatment of ischemic stroke …

Cardiovascular diseases (CVDs) refer to a collection of conditions characterized by
abnormalities in the cardiovascular system. They are a global problem and one of the …