[HTML][HTML] Role of vitamin K in chronic kidney disease: A focus on bone and cardiovascular health

F Bellone, M Cinquegrani, R Nicotera… - International Journal of …, 2022 - mdpi.com
Chronic kidney disease (CKD) is commonly associated with vitamin K deficiency. Some of
the serious complications of CKD are represented by cardiovascular disease (CVD) and …

[HTML][HTML] Role of vitamin K in CKD: is its supplementation advisable in CKD patients?

P Grzejszczak, I Kurnatowska - Kidney and Blood Pressure Research, 2021 - karger.com
Background: Patients with CKD are at an increased risk of developing vascular calcification
(VC) and bone complications which translate into a higher morbidity and mortality. The …

[HTML][HTML] The Pleiotropic Role of Vitamin K in Multimorbidity of Chronic Obstructive Pulmonary Disease

I Piscaer, R Janssen, FME Franssen… - Journal of Clinical …, 2023 - mdpi.com
Although defined by the presence of airflow obstruction and respiratory symptoms, patients
with chronic obstructive pulmonary disease (COPD) are characterized by multimorbidity …

[HTML][HTML] Kidney function-dependence of vitamin K-status parameters: Results from the transplantlines biobank and cohort studies

D Kremer, D Groothof, CA Keyzer, C Eelderink… - Nutrients, 2021 - mdpi.com
High circulating dephosphorylated (dp) uncarboxylated (uc) matrix Gla protein (MGP) and uc
osteocalcin (OC) concentrations are regarded as markers of vitamin K-deficiency. However …

[HTML][HTML] Causal relationship from heart failure to kidney function and CKD: A bidirectional two-sample mendelian randomization study

J Zhang, Z Hu, Y Tan, J Ye - Plos one, 2023 - journals.plos.org
Background Heart Failure (HF) is a widespread condition that affects millions of people, and
it is caused by issues with the heart and blood vessels. Even though we know hypertension …

[HTML][HTML] Plasma Dephosphorylated-Uncarboxylated Matrix Gla-Protein in Systemic Sclerosis Patients: Biomarker Potential for Vascular Calcification and Inflammation

J Potjewijd, R Tobal, KA Boomars, VVPM van Empel… - Diagnostics, 2023 - mdpi.com
Background: Systemic sclerosis (SSc) patients face an elevated risk of cardiovascular
disease (CVD), even when classic cardiovascular risk factors are considered. Plasma …

[HTML][HTML] Reply to Janssen et al. Comment on “Kremer et al. Kidney Function-Dependence of Vitamin K-Status Parameters: Results from the TransplantLines Biobank …

D Kremer, D Groothof, CA Keyzer, C Eelderink… - Nutrients, 2022 - mdpi.com
Nutrients | Free Full-Text | Reply to Janssen et al. Comment on “Kremer et al. Kidney
Function-Dependence of Vitamin K-Status Parameters: Results from the TransplantLines …

[HTML][HTML] Urinary matrix Gla protein is associated with mortality risk in Flemish population: A prospective study

D Wei, J Melgarejo, T Vanassche… - Frontiers in …, 2022 - frontiersin.org
Background: Vascular calcification is strongly related to the risk of mortality and
cardiovascular diseases. In vascular calcification, matrix Gla protein (MGP), a small vitamin …

Reduced vitamin K status and coronavirus disease 2019: an epiphenomenon of impaired kidney function?

D Groothof, A Post, ROB Gans… - Clinical Infectious …, 2021 - academic.oup.com
To the Editor—Dofferhoff et al [1] recently hypothesized that enhanced thrombogenicity
related to low vitamin K status is implicated in coronavirus disease 2019 (COVID-19), linking …

THE ASSOCIATION OF URINARY MATRIX GLA PROTEIN WITH CIRCULATING INACTIVE MATRIX GLA PROTEIN, RENAL FUNCTION AND MORTALITY RISK: A …

D Wei, J Melgarejo, T Vanassche… - Journal of …, 2022 - journals.lww.com
Objective: Matrix Gla protein (MGP) is a small protein for the protection of vascular
calcification. High circulating desphospho-uncarboxylated MGP (dp-ucMGP), indicative of …