Zinc: from biological functions to therapeutic potential
MI Costa, AB Sarmento-Ribeiro… - International Journal of …, 2023 - mdpi.com
The trace element zinc (Zn) displays a wide range of biological functions. Zn ions control
intercellular communication and intracellular events that maintain normal physiological …
intercellular communication and intracellular events that maintain normal physiological …
[HTML][HTML] European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)
Abstract The European Cooperation in Science and Technology (COST) provides an ideal
framework to establish multi-disciplinary research networks. COST Action BM1203 (EU …
framework to establish multi-disciplinary research networks. COST Action BM1203 (EU …
[HTML][HTML] From zinc homeostasis to disease progression: Unveiling the neurodegenerative puzzle
YG Fan, TY Wu, LX Zhao, RJ Jia, H Ren, WJ Hou… - Pharmacological …, 2024 - Elsevier
Zinc is a crucial trace element in the human body, playing a role in various physiological
processes such as oxidative stress, neurotransmission, protein synthesis, and DNA repair …
processes such as oxidative stress, neurotransmission, protein synthesis, and DNA repair …
Metal profiling in coronary ischemia-reperfusion injury: Implications for KEAP1/NRF2 regulated redox signaling
F Yang, MJ Smith - Free Radical Biology and Medicine, 2024 - Elsevier
Coronary ischemia-reperfusion (IR) injury results from a blockage of blood supply to the
heart followed by restoration of perfusion, leading to oxidative stress induced pathological …
heart followed by restoration of perfusion, leading to oxidative stress induced pathological …
Hyperglycemia-Induced Changes in ZIP7 and ZnT7 Expression Cause Zn2+ Release From the Sarco(endo)plasmic Reticulum and Mediate ER Stress in the Heart
Changes in cellular free Zn2+ concentration, including those in the sarco (endo) plasmic
reticulum [S (E) R], are primarily coordinated by Zn2+ transporters (ZnTs) whose identity and …
reticulum [S (E) R], are primarily coordinated by Zn2+ transporters (ZnTs) whose identity and …
Interactions between zinc and NRF2 in vascular redox signalling
F Yang, MJ Smith, RCM Siow… - Biochemical Society …, 2024 - portlandpress.com
Recent evidence highlights the importance of trace metal micronutrients such as zinc (Zn) in
coronary and vascular diseases. Zn2+ plays a signalling role in modulating endothelial nitric …
coronary and vascular diseases. Zn2+ plays a signalling role in modulating endothelial nitric …
[PDF][PDF] Zinc and zinc nanoparticles: biological role and application in biomedicine
KI Bogutska, YP Sklyarov… - Ukrainica bioorganica …, 2013 - bioorganica.org.ua
Due to nanodimension of functional components of living cells, the application of
nanotechnologies in biomedical purposes is an important problem for today. One of the most …
nanotechnologies in biomedical purposes is an important problem for today. One of the most …
Intracellular zinc modulates cardiac ryanodine receptor-mediated calcium release
Aberrant Zn 2+ homeostasis is a hallmark of certain cardiomyopathies associated with
altered contractile force. In this study, we addressed whether Zn 2+ modulates cardiac …
altered contractile force. In this study, we addressed whether Zn 2+ modulates cardiac …
Role of Scl39a13/ZIP13 in cardiovascular homeostasis
T Hara, I Yamada, T Ohashi, M Tamura, A Hijikata… - Plos one, 2022 - journals.plos.org
Zinc plays a critical role in many physiological processes, and disruption of zinc
homeostasis induces various disorders, such as growth retardation, osteopenia, immune …
homeostasis induces various disorders, such as growth retardation, osteopenia, immune …
[PDF][PDF] The critical roles of zinc: beyond impact on myocardial signaling
SR Lee, SJ Noh, JR Pronto, YJ Jeong… - The Korean journal …, 2015 - synapse.koreamed.org
Zinc has been considered as a vital constituent of proteins, including enzymes. Mobile
reactive zinc (Zn2+) is the key form of zinc involved in signal transductions, which are mainly …
reactive zinc (Zn2+) is the key form of zinc involved in signal transductions, which are mainly …