Engineering Protein Nanoparticles Functionalized with an Immunodominant Coxiella burnetii Antigen to Generate a Q Fever Vaccine
Coxiella burnetii is the causative agent of Q fever, for which there is yet to be an FDA-
approved vaccine. This bacterial pathogen has both extra-and intracellular stages in its life …
approved vaccine. This bacterial pathogen has both extra-and intracellular stages in its life …
Poly (I: C) and R848 ligands show better adjuvanticity to induce B and T cell responses against the antigen (s)
Abstract Poly (I: C) and R848, synthetic ligands that activate Toll-like receptor 3 (TLR3) and
TLR7/8 respectively, have been well-established for their ability to stimulate the immune …
TLR7/8 respectively, have been well-established for their ability to stimulate the immune …
Vaccine-induced adaptive T cell immunity enhances protective responses against Coxiella burnetii
S Jan - 2023 - search.proquest.com
Coxiella burnetii is an intracellular Gram-negative bacterium responsible for Q fever, a
zoonotic disease with significant global health implications courtesy of its endemic status …
zoonotic disease with significant global health implications courtesy of its endemic status …