History, discovery, and classification of lncRNAs
J Jarroux, A Morillon, M Pinskaya - Long non coding RNA biology, 2017 - Springer
Abstract The RNA World Hypothesis suggests that prebiotic life revolved around RNA
instead of DNA and proteins. Although modern cells have changed significantly in 4 billion …
instead of DNA and proteins. Although modern cells have changed significantly in 4 billion …
Unique features of long non-coding RNA biogenesis and function
Long non-coding RNAs (lncRNAs) are a diverse class of RNAs that engage in numerous
biological processes across every branch of life. Although initially discovered as mRNA-like …
biological processes across every branch of life. Although initially discovered as mRNA-like …
A high-resolution protein architecture of the budding yeast genome
The genome-wide architecture of chromatin-associated proteins that maintains chromosome
integrity and gene regulation is not well defined. Here we use chromatin …
integrity and gene regulation is not well defined. Here we use chromatin …
The Landscape of long noncoding RNA classification
GS Laurent, C Wahlestedt, P Kapranov - Trends in genetics, 2015 - cell.com
Advances in the depth and quality of transcriptome sequencing have revealed many new
classes of long noncoding RNAs (lncRNAs). lncRNA classification has mushroomed to …
classes of long noncoding RNAs (lncRNAs). lncRNA classification has mushroomed to …
Ten years of next-generation sequencing technology
EL Van Dijk, H Auger, Y Jaszczyszyn, C Thermes - Trends in genetics, 2014 - cell.com
Ten years ago next-generation sequencing (NGS) technologies appeared on the market.
During the past decade, tremendous progress has been made in terms of speed, read …
During the past decade, tremendous progress has been made in terms of speed, read …
Hijacked in cancer: the KMT2 (MLL) family of methyltransferases
Abstract Histone–lysine N-methyltransferase 2 (KMT2) family proteins methylate lysine 4 on
the histone H3 tail at important regulatory regions in the genome and thereby impart crucial …
the histone H3 tail at important regulatory regions in the genome and thereby impart crucial …
Learning the languages of the chloroplast: retrograde signaling and beyond
The chloroplast can act as an environmental sensor, communicating with the cell during
biogenesis and operation to change the expression of thousands of proteins. This process …
biogenesis and operation to change the expression of thousands of proteins. This process …
Molecular mechanisms of long noncoding RNAs
KC Wang, HY Chang - Molecular cell, 2011 - cell.com
Long noncoding RNAs (lncRNAs) are an important class of pervasive genes involved in a
variety of biological functions. Here we discuss the emerging archetypes of molecular …
variety of biological functions. Here we discuss the emerging archetypes of molecular …
Genome regulation by long noncoding RNAs
The central dogma of gene expression is that DNA is transcribed into messenger RNAs,
which in turn serve as the template for protein synthesis. The discovery of extensive …
which in turn serve as the template for protein synthesis. The discovery of extensive …
The emergence of lncRNAs in cancer biology
JR Prensner, AM Chinnaiyan - Cancer discovery, 2011 - AACR
The discovery of numerous noncoding RNA (ncRNA) transcripts in species from yeast to
mammals has dramatically altered our understanding of cell biology, especially the biology …
mammals has dramatically altered our understanding of cell biology, especially the biology …