Hyperuricemia and its related diseases: mechanisms and advances in therapy

L Du, Y Zong, H Li, Q Wang, L Xie, B Yang… - … and Targeted Therapy, 2024 - nature.com
Hyperuricemia, characterized by elevated levels of serum uric acid (SUA), is linked to a
spectrum of commodities such as gout, cardiovascular diseases, renal disorders, metabolic …

An overview of chronic kidney disease pathophysiology: The impact of gut dysbiosis and oral disease

S Altamura, D Pietropaoli, F Lombardi, R Del Pinto… - Biomedicines, 2023 - mdpi.com
Chronic kidney disease (CKD) is a severe condition and a significant public health issue
worldwide, carrying the burden of an increased risk of cardiovascular events and mortality …

Dispersant-free supra single-walled carbon nanotubes for simultaneous and highly sensitive biomolecule sensing in ex vivo mouse tissues

R Manikandan, J Kim, A Ishigami, JY Cho, JH Kim… - Carbon, 2023 - Elsevier
A simple sensing methodology for rapid detection of multiple biomolecules in human health
diagnostics remains a significant challenge. Herein, we developed a novel dispersant-free …

Hyperuricemia and gout increased the risk of long-term mortality in patients with heart failure: insights from the National Health and Nutrition Examination Survey

Y Han, Y Cao, X Han, H Di, Y Yin, J Wu… - Journal of Translational …, 2023 - Springer
Background The prevalence of hyperuricemia, gout, and heart failure (HF) is on the rise, and
these conditions often share similar risk factors. The present study aimed to evaluate the …

Serum metabolomics of hyperbilirubinemia and hyperuricemia in the Tibetan plateau has unique characteristics

H Zhang, X Ma, J Xu, P Jin, L Yang, Y Pan, F Yin… - Scientific Reports, 2023 - nature.com
Few studies have provided data on the metabolomics characteristics of metabolic diseases
such as hyperuricemia and hyperbilirubinemia in the Tibetan plateau. In the current study …

Insights into the relationship between serum uric acid and pulmonary hypertension

Y Zhou, M Chen, J Zheng, X Shui… - Molecular …, 2023 - spandidos-publications.com
Pulmonary hypertension (PH) is a progressive lethal disease, which is characterized by
abnormal vascular remodeling and persistently elevated pulmonary artery pressure …

Ferulic acid supplementation alleviates hyperuricemia in high-fructose/fat diet-fed rats via promoting uric acid excretion and mediating the gut microbiota

N Zhang, J Zhou, L Zhao, Z Zhao, S Wang, L Zhang… - Food & Function, 2023 - pubs.rsc.org
The prevalence of hyperuricemia (HUA) has been rising, and it is typically accompanied by
renal injury and intestinal flora disorder, leading to a non-negligible health crisis. Ferulic …

Exploring the mechanism underlying hyperuricemia using comprehensive research on multi-omics

H Liu, R Xie, Q Dai, J Fang, Y Xu, B Li - Scientific Reports, 2023 - nature.com
Hyperuricemia involves multiple complex metabolisms, but no study has conducted a
comprehensive analysis using human blood and urine metabolomics for hyperuricemia …

Associations between composite dietary antioxidant index and gout: national health and nutrition examination survey 2007–2018

W Hu, Z Ye, T Li, Z Shi - Biological Research For Nursing, 2024 - journals.sagepub.com
Introduction: To explore the relationship between the composite dietary antioxidant index
(CDAI) and gout to provide support for preventing gout through dietary intervention …

The potential relationship of coronary artery disease and hyperuricemia: A cardiometabolic risk factor

K Li, K Li, Q Yao, X Shui, J Zheng, Y He, W Lei - Heliyon, 2023 - cell.com
Coronary arterial disease (CAD) is the leading cause of mortality in the world.
Hyperuricemia has recently emerged as a novel independent risk factor of CAD, in addition …