Simple Summary Understanding how genes are regulated is a vital area of current
biological research and a crucial adjunct to ongoing efforts to sequence entire genomes …

Enhancers are short deoxyribonucleic acid fragments that assume an important part in the
genetic process of gene expression. Due to their possibly distant location relative to the …

Simple Summary Insects comprise the largest and most diverse class of animals on earth,
and have major impacts on human health and agriculture. The effort to better understand …

Plasma metabolic profiles were compared between patients with hypertension with and
without left ventricular hypertrophy and significantly decreased oleic acid (OA) levels were …

Background Predicting cis-regulatory modules (CRMs) in a genome and their functional
states in various cell/tissue types of the organism are two related challenging computational …

Abstract cis-regulatory modules (CRMs) formed by clusters of transcription factor (TF)
binding sites (TFBSs) are as important as coding sequences in specifying phenotypes of …

Background Mouse is probably the most important model organism to study mammal
biology and human diseases. A better understanding of the mouse genome will help …

Transcription factors (TFs) play a key role in development and in cellular responses to the
environment by activating or repressing the transcription of target genes in precise spatial …

Background Identifying transcriptional enhancers and other cis-regulatory modules (CRMs)
is an important goal of post-sequencing genome annotation. Computational approaches …

The completion of insect genome sequencing projects has generated vast amounts of
genetic data, but the process of comprehensive annotation, particularly of non-coding …