Objectives: To describe three methods used to screen for frameshift mutations in exon 9 of
the CALR gene. Methods: Genomic DNA from 47 patients was extracted from peripheral …

The myeloproliferative neoplasms are chronic myeloid cancers divided in Philadelphia
positive (Ph+), chronic myeloid leukemia, or negative: polycythemia vera (PV) essential …

AB hematopoietic progenitors is theoretically associated with a risk (though possibly low) of
disease progression, underscoring the need for regular follow up. Consequently, a frequent …

Inflammatory stimuli have divergent effects on peripheral platelet counts, although the
mechanisms of thrombocytopenic and thrombocytotic responses remain poorly understood …

Background Calreticulin (CALR) gene mutations are currently recommended as biomarkers
in diagnosis of patients with myeloproliferative neoplasms (MPN) with Jak2 V617F negative …

The identification of acquired CALR mutations in patients with essential thrombocythaemia
(ET) or myelofibrosis (MF) has meant that disease‐initiating mutations can now be detected …

Myelodysplastic syndrome and myeloproliferative neoplasms are clonal myeloid disorders
arising from haematopoietic stem cells that have the tendency to progress into acute myeloid …

Objectives: The primary objective was to determine the prevalence of calreticulin (CALR)
mutation in patients with non-JAK2 V617F mutated essential thrombocythemia (ET). The …

Calreticulin (CALR) mutations are included in the WHO diagnostic criteria of
Myeloproliferative Neoplasm (MPN). Presence of CALR mutation, aids in their diagnosis by …

Capricious CALR mutated clones in myeloproliferative neoplasms. - Abstract - Europe PMC
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