[HTML][HTML] A Novel Pyrazole Exhibits Potent Anticancer Cytotoxicity via Apoptosis, Cell Cycle Arrest, and the Inhibition of Tubulin Polymerization in Triple-Negative …

EA Borrego, CD Guerena, AY Schiaffino Bustamante… - Cells, 2024 - mdpi.com
In this study, we screened a chemical library to find potent anticancer compounds that are
less cytotoxic to non-cancerous cells. This study revealed that pyrazole PTA-1 is a potent …

N-Benzyl-r-2, c-6-diphenylpiperidines: Synthesis, Spectral characterization, Conformational Analysis and Evaluation of Biological Activities

P Chandrika, S Sethuvasan, P Santhosh… - Journal of Molecular …, 2025 - Elsevier
Abstract Six new N-benzyl-2, 6-diphenylpiperidines 13-18 have been synthesized. The
newly synthesized compounds are characterized using mass, IR, 1D NMR and selected …

In vitro Characterization of Novel Compounds with Anti-cancer Activity

EAB Puerta - 2022 - search.proquest.com
Two libraries of chemical compounds were analyzed for their cytotoxic activity against
cancer and non-cancerous cell lines. In chapter 1, fourteen novel piperidones were tested …

Two Novel Piperidone Compounds Display Antiproliferative Effects on Human Prostate and Lymphoma Cancer Cell Lines and in vitro Investigation of …

RM Swain - 2022 - search.proquest.com
Tumor interactions predominantly dominate cancer progression and its tumor
microenvironment. Such interactions include, tumors generating signals that cause …

In Vitro Characterization Of Novel Compounds With Anti-Cancer Activity

EA Borrego Puerta - 2022 - scholarworks.utep.edu
Two libraries of chemical compounds were analyzed for their cytotoxic activity against
cancer and non-cancerous cell lines. In chapter 1, fourteen novel piperidones were tested …