Biodelivery of therapeutic extracellular vesicles: should mononuclear phagocytes always be feared?
M Cieślik, K Bryniarski, K Nazimek - Frontiers in Cell and …, 2023 - frontiersin.org
At present, extracellular vesicles (EVs) are considered key candidates for cell-free therapies,
including treatment of allergic and autoimmune diseases. However, their therapeutic …
including treatment of allergic and autoimmune diseases. However, their therapeutic …
[PDF][PDF] Update on innate and adaptive immunity in cystic fibrosis
EM Bruscia, TL Bonfield - Clinics in Chest Medicine, 2022 - Elsevier
Cystic fibrosis (CF) pathophysiology is hallmarked by excessive inflammation and the
inability to efficiently resolve lung infections, contributing to morbidly and eventually the …
inability to efficiently resolve lung infections, contributing to morbidly and eventually the …
Extracellular vesicles: Recent insights into the interaction between host and pathogenic bacteria
C Zou, Y Zhang, H Liu, Y Wu, X Zhou - Frontiers in Immunology, 2022 - frontiersin.org
Extracellular vesicles (EVs) are nanosized lipid particles released by virtually every living
cell. EVs carry bioactive molecules, shuttle from cells to cells and transduce signals …
cell. EVs carry bioactive molecules, shuttle from cells to cells and transduce signals …
Lung Inflammatory Genes in Cystic Fibrosis and Their Relevance to Cystic Fibrosis Transmembrane Conductance Regulator Modulator Therapies
A Carbone, P Vitullo, S Di Gioia, M Conese - Genes, 2023 - mdpi.com
Cystic fibrosis (CF) is a monogenic syndrome determined by over 2000 mutations in the CF
Transmembrane Conductance Regulator (CFTR) gene harbored on chromosome 7. In …
Transmembrane Conductance Regulator (CFTR) gene harbored on chromosome 7. In …
Small extracellular vesicles derived from umbilical cord mesenchymal stem cells repair blood-spinal cord barrier disruption after spinal cord injury through down …
C Xue, X Ma, X Guan, H Feng, M Zheng, X Yang - PeerJ, 2023 - peerj.com
Spinal cord injury could cause irreversible neurological dysfunction by destroying the blood-
spinal cord barrier (BSCB) and allowing blood cells like neutrophils and macrophages to …
spinal cord barrier (BSCB) and allowing blood cells like neutrophils and macrophages to …
Extracellular vesicles secreted by primary human bronchial epithelial cells reduce Pseudomonas aeruginosa burden and inflammation in cystic fibrosis mouse lung
S Sarkar, R Barnaby, AB Nymon… - … of Physiology-Lung …, 2024 - journals.physiology.org
Cystic fibrosis (CF) results in a reduction in the volume of airway surface liquid, increased
accumulation of viscous mucus, persistent antibiotic-resistant lung infections that cause …
accumulation of viscous mucus, persistent antibiotic-resistant lung infections that cause …
[HTML][HTML] Targeting Airway Immunity in Lung Disease: Extracellular vesicles secreted by primary human bronchial epithelial cells reduce Pseudomonas aeruginosa …
S Sarkar, R Barnaby, AB Nymon… - American Journal of …, 2024 - ncbi.nlm.nih.gov
Cystic fibrosis (CF) results in a reduction in the volume of airway surface liquid, increased
accumulation of viscous mucus, persistent antibiotic-resistant lung infections that cause …
accumulation of viscous mucus, persistent antibiotic-resistant lung infections that cause …
[HTML][HTML] Extracellular Vesicles in Lung Health, Disease, and Therapy: An rRNA fragment in extracellular vesicles secreted by human airway epithelial cells increases …
K Koeppen, TH Hampton, R Barnaby… - American Journal of …, 2023 - ncbi.nlm.nih.gov
Lung infections caused by antibiotic-resistant strains of Pseudomonas aeruginosa are
difficult to eradicate in immunocompromised hosts such as those with cystic fibrosis. We …
difficult to eradicate in immunocompromised hosts such as those with cystic fibrosis. We …
Modulation of Plasmatic Matrix Metalloprotease 9: A Promising New Tool for Understanding the Variable Clinical Responses of Patients with Cystic Fibrosis to Cystic …
M Capraro, M Pedrazzi, R De Tullio… - International Journal of …, 2023 - mdpi.com
Background: The most recent modulator combination, elexacaftor/tezacaftor/ivacaftor
(Trikafta®), has been shown to improve clinical outcomes in most patients with cystic fibrosis …
(Trikafta®), has been shown to improve clinical outcomes in most patients with cystic fibrosis …
An rRNA fragment in extracellular vesicles secreted by human airway epithelial cells increases the fluoroquinolone sensitivity of P. aeruginosa
K Koeppen, TH Hampton, R Barnaby… - … of Physiology-Lung …, 2023 - journals.physiology.org
Lung infections caused by antibiotic-resistant strains of Pseudomonas aeruginosa are
difficult to eradicate in immunocompromised hosts such as those with cystic fibrosis. We …
difficult to eradicate in immunocompromised hosts such as those with cystic fibrosis. We …