The COMPASS family of histone H3K4 methylases: mechanisms of regulation in development and disease pathogenesis
A Shilatifard - Annual review of biochemistry, 2012 - annualreviews.org
The Saccharomyces cerevisiae Set1/COMPASS was the first histone H3 lysine 4 (H3K4)
methylase identified over 10 years ago. Since then, it has been demonstrated that …
methylase identified over 10 years ago. Since then, it has been demonstrated that …
Regulation of Cell Wall Biogenesis in Saccharomyces cerevisiae: The Cell Wall Integrity Signaling Pathway
DE Levin - Genetics, 2011 - academic.oup.com
The yeast cell wall is a strong, but elastic, structure that is essential not only for the
maintenance of cell shape and integrity, but also for progression through the cell cycle …
maintenance of cell shape and integrity, but also for progression through the cell cycle …
Targeted recruitment of Set1 histone methylase by elongating Pol II provides a localized mark and memory of recent transcriptional activity
Set1, the yeast histone H3-lysine 4 (H3-K4) methylase, is recruited by the Pol II elongation
machinery to a highly localized domain at the 5′ portion of active mRNA coding regions …
machinery to a highly localized domain at the 5′ portion of active mRNA coding regions …
The Paf1 complex is required for histone H3 methylation by COMPASS and Dot1p: linking transcriptional elongation to histone methylation
NJ Krogan, J Dover, A Wood, J Schneider, J Heidt… - Molecular cell, 2003 - cell.com
Methylation of histone proteins is one of their many modifications that affect chromatin
structure and regulate gene expression. Methylation of histone H3 on lysines 4 and 79 …
structure and regulate gene expression. Methylation of histone H3 on lysines 4 and 79 …
Methylation of histone H3 by Set2 in Saccharomyces cerevisiae is linked to transcriptional elongation by RNA polymerase II
Set2 methylates Lys36 of histone H3. We show here that yeast Set2 copurifies with RNA
polymerase II (RNAPII). Chromatin immunoprecipitation analyses demonstrated that Set2 …
polymerase II (RNAPII). Chromatin immunoprecipitation analyses demonstrated that Set2 …
The Paf1 complex: a keystone of nuclear regulation operating at the interface of transcription and chromatin
The regulation of transcription by RNA polymerase II is closely intertwined with the
regulation of chromatin structure. A host of proteins required for the disassembly …
regulation of chromatin structure. A host of proteins required for the disassembly …
Elongation by RNA polymerase II: the short and long of it
RJ Sims, R Belotserkovskaya… - Genes & …, 2004 - genesdev.cshlp.org
Appreciable advances into the process of transcript elongation by RNA polymerase II (RNAP
II) have identified this stage as a dynamic and highly regulated step of the transcription …
II) have identified this stage as a dynamic and highly regulated step of the transcription …
RNA Polymerase II Elongation Factors of Saccharomyces cerevisiae: a Targeted Proteomics Approach
To physically characterize the web of interactions connecting the Saccharomyces cerevisiae
proteins suspected to be RNA polymerase II (RNAPII) elongation factors, subunits of …
proteins suspected to be RNA polymerase II (RNAPII) elongation factors, subunits of …
Emerging insights into the roles of the Paf1 complex in gene regulation
The conserved, multifunctional Polymerase-Associated Factor 1 complex (Paf1C) regulates
all stages of the RNA polymerase (Pol) II transcription cycle. In this review, we examine a …
all stages of the RNA polymerase (Pol) II transcription cycle. In this review, we examine a …
[HTML][HTML] Chromatin remodeling protein Chd1 interacts with transcription elongation factors and localizes to transcribed genes
R Simic, DL Lindstrom, HG Tran, KL Roinick… - The EMBO …, 2003 - embopress.org
Transcription in eukaryotes is influenced by the chromatin state of the template, and
chromatin remodeling factors have well‐documented roles in regulating transcription …
chromatin remodeling factors have well‐documented roles in regulating transcription …