Mass spectrometry as a quantitative tool in plant metabolomics

TF Jorge, AT Mata, C António - … Transactions of the …, 2016 - royalsocietypublishing.org
Metabolomics is a research field used to acquire comprehensive information on the
composition of a metabolite pool to provide a functional screen of the cellular state. Studies …

Capillary electrophoresis

RK Harstad, AC Johnson, MM Weisenberger… - Analytical …, 2016 - ACS Publications
Capillary electrophoresis (CE) is a field that continues to grow. All areas of CE including
theory, separation modes, instrumentation, and applications remain active areas of …

Fructose-1, 6-bisphosphate and aldolase mediate glucose sensing by AMPK

CS Zhang, SA Hawley, Y Zong, M Li, Z Wang, A Gray… - Nature, 2017 - nature.com
The major energy source for most cells is glucose, from which ATP is generated via
glycolysis and/or oxidative metabolism. Glucose deprivation activates AMP-activated protein …

Hierarchical activation of compartmentalized pools of AMPK depends on severity of nutrient or energy stress

Y Zong, CS Zhang, M Li, W Wang, Z Wang, SA Hawley… - Cell Research, 2019 - nature.com
AMPK, a master regulator of metabolic homeostasis, is activated by both AMP-dependent
and AMP-independent mechanisms. The conditions under which these different …

Comprehensive investigation of tobacco leaves during natural early senescence via multi-platform metabolomics analyses

L Li, J Zhao, Y Zhao, X Lu, Z Zhou, C Zhao, G Xu - Scientific reports, 2016 - nature.com
Senescence is the final stage of leaf growth and development. Many different physiological
activities occur during this process. A comprehensive metabolomics analysis of tobacco …

Transient receptor potential V channels are essential for glucose sensing by aldolase and AMPK

M Li, CS Zhang, Y Zong, JW Feng, T Ma, M Hu, Z Lin… - Cell metabolism, 2019 - cell.com
Summary Fructose-1, 6-bisphosphate (FBP) aldolase links sensing of declining glucose
availability to AMPK activation via the lysosomal pathway. However, how aldolase transmits …

[HTML][HTML] A metabolomics study delineating geographical location-associated primary metabolic changes in the leaves of growing tobacco plants by GC-MS and CE …

Y Zhao, J Zhao, C Zhao, H Zhou, Y Li, J Zhang, L Li… - Scientific reports, 2015 - nature.com
Ecological conditions and developmental senescence significantly affect the physiological
metabolism of plants, yet relatively little is known about the influence of geographical …

Plant metabolomics: maximizing metabolome coverage by optimizing mobile phase additives for nontargeted mass spectrometry in positive and negative electrospray …

M Creydt, M Fischer - Analytical chemistry, 2017 - ACS Publications
Nontargeted screening methods with ultrahigh-performance liquid chromatography-
electrospray ionization/quadrupole-time-of-flight mass spectrometry have been extensively …

Metabolic profiling of tobacco leaves at different growth stages or different stalk positions by gas chromatography–mass spectrometry

L Zhang, X Zhang, H Ji, W Wang, J Liu, F Wang… - Industrial Crops and …, 2018 - Elsevier
The dynamic and temporal changes in tobacco leaf metabolites can have an immense
impact on their compositions, which are closely related to the quality and flavor of the …

Food authentication: Small-molecule profiling as a tool for the geographic discrimination of German white asparagus

M Creydt, D Hudzik, M Rurik… - Journal of agricultural …, 2018 - ACS Publications
For the first time, a non-targeted metabolomics approach by means of ultraperformance
liquid chromatography coupled to electrospray quadruple time-of-flight mass spectrometry …