Virus-like particles as a highly efficient vaccine platform: diversity of targets and production systems and advances in clinical development

N Kushnir, SJ Streatfield, V Yusibov - Vaccine, 2012 - Elsevier
Virus-like particles (VLPs) are a class of subunit vaccines that differentiate themselves from
soluble recombinant antigens by stronger protective immunogenicity associated with the …

Yeast-based vaccines: New perspective in vaccine development and application

R Kumar, P Kumar - FEMS yeast Research, 2019 - academic.oup.com
In presently licensed vaccines, killed or attenuated organisms act as a source of
immunogens except for peptide-based vaccines. These conventional vaccines required a …

How far have we explored fungi to fight cancer?

CW How, YS Ong, SS Low, A Pandey, PL Show… - Seminars in cancer …, 2022 - Elsevier
The use of fungal cultures have been well documented in human history. Although its used
in healthcare, like penicillin and statins, have saved countless of lives, but there is still no …

Different applications of virus‐like particles in biology and medicine: vaccination and delivery systems

Z Shirbaghaee, A Bolhassani - Biopolymers, 2016 - Wiley Online Library
Virus‐like particles (VLPs) mimic the whole construct of virus particles devoid of viral
genome as used in subunit vaccine design. VLPs can elicit efficient protective immunity as …

[HTML][HTML] Yeast-based virus-like particles as an emerging platform for vaccine development and delivery

V Srivastava, KN Nand, A Ahmad, R Kumar - Vaccines, 2023 - mdpi.com
Virus-like particles (VLPs) are empty, nanoscale structures morphologically resembling
viruses. Internal cavity, noninfectious, and particulate nature with a high density of repeating …

Hepatitis C viral life cycle

T Suzuki, K Ishii, H Aizaki, T Wakita - Advanced drug delivery reviews, 2007 - Elsevier
Hepatitis C virus (HCV) has been recognized as a major cause of chronic liver diseases
worldwide. Molecular studies of the virus became possible with the successful cloning of its …

[HTML][HTML] HCV genome and life cycle

S Chevaliez, JM Pawlotsky - Hepatitis C viruses: genomes and …, 2006 - ncbi.nlm.nih.gov
Hepatitis C virus (HCV) infection afflicts more than 170 million people worldwide, with the
great majority of patients with acute hepatitis C developing chronic HCV infection. It can …

Molecular biology of hepatitis C virus

T Suzuki, H Aizaki, K Murakami, I Shoji… - Journal of …, 2007 - Springer
Infection with hepatitis C virus (HCV), which is distributed worldwide, often becomes
persistent, causing chronic hepatitis, cirrhosis, and hepatocellular carcinoma. For many …

[PDF][PDF] Virus like particles as immunogens and universal nanocarriers

A Naskalska, K Pyrć - 2015 - ruj.uj.edu.pl
Over the last two decades virus‑like particles (VLPs) have become an important tool in
biomedical research and medicine. VLPs are multi‑protein structures that resemble viable …

[HTML][HTML] Preclinical development and production of virus-like particles as vaccine candidates for hepatitis C

MG Masavuli, DK Wijesundara, J Torresi… - Frontiers in …, 2017 - frontiersin.org
Hepatitis C Virus (HCV) infects 2% of the world's population and is the leading cause of liver
disease and liver transplantation. It poses a serious and growing worldwide public health …