Versatile synthetic platform for 1, 2, 3-triazole chemistry

DP Vala, RM Vala, HM Patel - Acs Omega, 2022 - ACS Publications
1, 2, 3-Triazole scaffolds are not obtained in nature, but they are still intensely investigated
by synthetic chemists in various fields due to their excellent properties and green synthetic …

Recent advances in the synthesis of heterocycles via reactions involving elemental sulfur

TB Nguyen - Advanced Synthesis & Catalysis, 2020 - Wiley Online Library
It is well known that heterocycles are among the most significant molecules for everyday life,
ranging from natural products and bioactive substances to functional materials. This review …

Recent advances in organic synthesis applying elemental selenium

T Guo, Z Li, L Bi, L Fan, P Zhang - Tetrahedron, 2022 - Elsevier
The synthesis of organoselenium compounds through C–Se bond-forming has attracted
immense attention due to their biological values and extensive pharmaceutical applications …

Cu-catalyzed azide–alkyne–thiol reaction forms ubiquitous background in chemical proteomic studies

A Wiest, P Kielkowski - Journal of the American Chemical Society, 2024 - ACS Publications
We report here a Cu-catalyzed azide–alkyne–thiol reaction forming thiotriazoles as the
major byproduct under widely used bio-orthogonal protein labeling “click” conditions. The …

[HTML][HTML] Azides in the Synthesis of Various Heterocycles

AEAA Nayl, AA Aly, WAA Arafa, IM Ahmed… - Molecules, 2022 - mdpi.com
In this review, we focus on some interesting and recent examples of various applications of
organic azides such as their intermolecular or intramolecular, under thermal, catalyzed, or …

Copper (i)-catalyzed multicomponent interrupted click reaction: modular synthesis of triazole sulfides from elemental sulfur

P Sun, W Wang, J Lai, H Yan, CH Tung… - Organic Chemistry …, 2023 - pubs.rsc.org
Organic synthesis of complex molecules from basic chemicals is one of the most attractive
approaches. We report herein the development of a new multicomponent copper (I) …

[HTML][HTML] One-pot multicomponent polymerization, metal-, and non-metal-catalyzed synthesis of organoselenium compounds

S Shaaban, HMA El-Lateef, MM Khalaf, M Gouda… - Polymers, 2022 - mdpi.com
The one-pot multicomponent synthetic strategy of organoselenium compounds represents
an alternative and robust protocol to the conventional multistep methods. During the last …

Copper-Mediated Intramolecular Interrupted CuAAC Selanylation

WKO Teixeira, DY de Albuquerque… - The Journal of …, 2023 - ACS Publications
We, herein, describe a copper-mediated domino CuAAC intramolecular selanylation for the
synthesis of unprecedented fused benzo [4, 5][1, 3] selenazolo [3, 2-c][1, 2, 3] triazoles from …

Each Interruption is an Opportunity: Novel Synthetic Strategies Explored Through Interrupted Click Reactions

F Brunelli, C Russo, M Giustiniano… - Chemistry–A European …, 2024 - Wiley Online Library
The particular and unique mechanism of the copper‐catalyzed reaction between azides and
alkynes (CuAAC) has not only allowed for the efficient synthesis of 1, 2, 3‐trisubstituted 1, 4 …

Three-Step Synthetic Pathway toward Fully Decorated [1,2,3]Triazolo[4,5-d]pyrimidine (8-Azapurine) Derivatives

F Reniers, S Anthonissen, L Van Meervelt… - Organic …, 2023 - ACS Publications
[1, 2, 3] Triazolo [4, 5-d] pyrimidines (8-azapurines) are known bioisosteres of the purine
nucleus. A step-efficient synthesis of 8-azapurines, in particular 6-alkyl derivatives, is …