Persisters refer to genetically drug susceptible quiescent (non-growing or slow growing)
bacteria that survive in stress environments such as antibiotic exposure, acidic and …

BACKGROUND The escalating crisis of multidrug resistance is raising fears of untreatable
infections caused by bacterial “superbugs.” However, many patients already suffer from …

Persisters are transiently tolerant variants that allow populations to avoid eradication by
antibiotic treatment. Their antibiotic tolerance is non-genetic, not inheritable and results from …

Within bacterial populations, a small fraction of persister cells is transiently capable of
surviving exposure to lethal doses of antibiotics. As a bet-hedging strategy, persistence …

Persisters are a small fraction of quiescent bacterial cells that survive lethal antibiotics or
stresses but can regrow under appropriate conditions. Persisters underlie persistent and …

Mycobacterial persisters, the survivors from antibiotic exposure, necessitate the lengthy
treatment of tuberculosis (TB) and pose a significant challenge for our control of the disease …

Bacterial persisters are phenotypic variants with extraordinary tolerances toward antibiotics.
Persister survival has been attributed to inhibition of essential cell functions during antibiotic …

The antibiotic tolerances of bacterial persisters have been attributed to transient dormancy.
While persisters have been observed to be growth inhibited prior to antibiotic exposure, we …

Persisters are transiently nongrowing and antibiotic-tolerant phenotypic variants identified in
major human pathogens, including intracellular Staphylococcus aureus. Due to their …

Persister cells constitute a small subpopulation of bacteria that display remarkably high
antibiotic tolerance and for pathogens such as Staphylococcus aureus are suspected as …