Intrinsic membrane permeability to small molecules
Spontaneous solute and solvent permeation through membranes is of vital importance to
human life, be it gas exchange in red blood cells, metabolite excretion, drug/toxin uptake, or …
human life, be it gas exchange in red blood cells, metabolite excretion, drug/toxin uptake, or …
Aquaporin‐Based Biomimetic Membranes for Low Energy Water Desalination and Separation Applications
A Azarafza, MA Islam… - Advanced Functional …, 2023 - Wiley Online Library
The emergence of biomimetic materials developed using nature's inspiration and biological
domains can drive a paradigm shift in the design and operation of future‐generation …
domains can drive a paradigm shift in the design and operation of future‐generation …
[HTML][HTML] Recent applications of fluorescence correlation spectroscopy in live systems
R Macháň, T Wohland - FEBS letters, 2014 - Elsevier
Fluorescence correlation spectroscopy (FCS) is a widely used technique in biophysics and
has helped address many questions in the life sciences. It provides important advantages …
has helped address many questions in the life sciences. It provides important advantages …
Shrinking gate fluorescence correlation spectroscopy yields equilibrium constants and separates photophysics from structural dynamics
T Schröder, J Bohlen, SE Ochmann… - Proceedings of the …, 2023 - National Acad Sciences
Fluorescence correlation spectroscopy is a versatile tool for studying fast conformational
changes of biomolecules especially when combined with Förster resonance energy transfer …
changes of biomolecules especially when combined with Förster resonance energy transfer …
Single-file transport of water through membrane channels
Water at interfaces governs many processes on the molecular scale from electrochemical
and enzymatic reactions to protein folding. Here we focus on water transport through …
and enzymatic reactions to protein folding. Here we focus on water transport through …
Ant1 activation and inhibition patterns support the fatty acid cycling mechanism for proton transport
Adenine nucleotide translocase (ANT) is a well-known mitochondrial exchanger of ATP
against ADP. In contrast, few studies have shown that ANT also mediates proton transport …
against ADP. In contrast, few studies have shown that ANT also mediates proton transport …
The hidden intricacies of aquaporins: remarkable details in a common structural scaffold
Evolution turned aquaporins (AQPs) into the most efficient facilitators of passive water flow
through cell membranes at no expense of solute discrimination. In spite of a plethora of …
through cell membranes at no expense of solute discrimination. In spite of a plethora of …
Quantification of water flux in vesicular systems
Water transport across lipid membranes is fundamental to all forms of life and plays a major
role in health and disease. However, not only typical water facilitators like aquaporins …
role in health and disease. However, not only typical water facilitators like aquaporins …
Filter gate closure inhibits ion but not water transport through potassium channels
T Hoomann, N Jahnke, A Horner… - Proceedings of the …, 2013 - National Acad Sciences
The selectivity filter of K+ channels is conserved throughout all kingdoms of life. Carbonyl
groups of highly conserved amino acids point toward the lumen to act as surrogates for the …
groups of highly conserved amino acids point toward the lumen to act as surrogates for the …
The sodium glucose cotransporter SGLT1 is an extremely efficient facilitator of passive water transport
The small intestine is void of aquaporins adept at facilitating vectorial water transport, and
yet it reabsorbs∼ 8 liters of fluid daily. Implications of the sodium glucose cotransporter …
yet it reabsorbs∼ 8 liters of fluid daily. Implications of the sodium glucose cotransporter …