Improving translation of animal models of addiction and relapse by reverse translation
Critical features of human addiction are increasingly being incorporated into complementary
animal models, including escalation of drug intake, punished drug seeking and taking …
animal models, including escalation of drug intake, punished drug seeking and taking …
The treatment of cocaine use disorder
KM Kampman - Science advances, 2019 - science.org
Cocaine use continues to be a serious worldwide public health problem. Cocaine abuse is
associated with substantial morbidity and mortality. Cocaine overdose deaths are increasing …
associated with substantial morbidity and mortality. Cocaine overdose deaths are increasing …
Pharmacotherapeutic strategies for treating cocaine use disorder—what do we have to offer?
Background Cocaine use contines to be a significant public health problem world‐wide.
However, despite substantial research efforts, no pharmacotherapies are approved for the …
However, despite substantial research efforts, no pharmacotherapies are approved for the …
Evaluation of the “pipeline” for development of medications for cocaine use disorder: a review of translational preclinical, human laboratory, and clinical trial research
Cocaine use disorder is a persistent public health problem for which no widely effective
medications exist. Self-administration procedures, which have shown good predictive …
medications exist. Self-administration procedures, which have shown good predictive …
Potential effect of antidepressants on remission from cocaine use disorder–A nationwide matched retrospective cohort study
Z Gao, TJ Winhusen, M Gorenflo, UE Ghitza… - Drug and alcohol …, 2023 - Elsevier
Background Cocaine use disorder (CUD) is a significant public health issue for which there
is no Food and Drug Administration-approved pharmacotherapy. Depressive disorders are …
is no Food and Drug Administration-approved pharmacotherapy. Depressive disorders are …
Contingency management plus acceptance and commitment therapy for initial cocaine abstinence: Results of a sequential multiple assignment randomized trial …
Background This study tested an adaptive intervention for optimizing abstinence outcomes
over phases of treatment for cocaine use disorder using a SMART design. Phase 1 …
over phases of treatment for cocaine use disorder using a SMART design. Phase 1 …
Psychostimulant use disorder, an unmet therapeutic goal: can modafinil narrow the gap?
M Hersey, AK Bacon, LG Bailey… - Frontiers in …, 2021 - frontiersin.org
The number of individuals affected by psychostimulant use disorder (PSUD) has increased
rapidly over the last few decades resulting in economic, emotional, and physical burdens on …
rapidly over the last few decades resulting in economic, emotional, and physical burdens on …
Cocaine choice procedures in animals, humans, and treatment-seekers: Can we bridge the divide?
SJ Moeller, WW Stoops - Pharmacology Biochemistry and Behavior, 2015 - Elsevier
Individuals with cocaine use disorder chronically self-administer cocaine to the detriment of
other rewarding activities, a phenomenon best modeled in laboratory drug-choice …
other rewarding activities, a phenomenon best modeled in laboratory drug-choice …
Poorer drinking outcomes with citalopram treatment for alcohol dependence: a randomized, double‐blind, placebo‐controlled trial
DA Charney, LM Heath, E Zikos… - Alcoholism: Clinical …, 2015 - Wiley Online Library
Background Previous research on the use of selective serotonin reuptake inhibitors (SSRIs)
as a treatment for alcohol dependence has yielded mixed results. Depression has been …
as a treatment for alcohol dependence has yielded mixed results. Depression has been …
Modafinil treatment of cocaine dependence: a systematic review and meta-analysis
Background: Currently, there is none FDA-approved medication to treat cocaine
dependency. Studies conducted with various medications, including antipsychotics …
dependency. Studies conducted with various medications, including antipsychotics …