[HTML][HTML] MHC class II complexes sample intermediate states along the peptide exchange pathway
M Wieczorek, J Sticht, S Stolzenberg, S Günther… - Nature …, 2016 - nature.com
The presentation of peptide-MHCII complexes (pMHCIIs) for surveillance by T cells is a well-
known immunological concept in vertebrates, yet the conformational dynamics of antigen …
known immunological concept in vertebrates, yet the conformational dynamics of antigen …
Side-chain conformational preferences govern protein–protein interactions
Protein secondary structures serve as geometrically constrained scaffolds for the display of
key interacting residues at protein interfaces. Given the critical role of secondary structures …
key interacting residues at protein interfaces. Given the critical role of secondary structures …
Immunomodulatory properties and in vivo osteogenesis of human dental stem cells from fresh and cryopreserved dental follicles
YH Kang, HJ Lee, SJ Jang, JH Byun, JS Lee, HC Lee… - Differentiation, 2015 - Elsevier
In our previous study, dental follicle tissues from extracted wisdom teeth were successfully
cryopreserved for use as a source of stem cells. The goals of the present study were to …
cryopreserved for use as a source of stem cells. The goals of the present study were to …
[HTML][HTML] A newly recognized pairing mechanism of the α-and β-chains of the chicken peptide–MHC class II complex
L Zhang, X Li, L Ma, B Zhang, G Meng… - The Journal of …, 2020 - journals.aai.org
Abstract MHC class II (MHC-II) molecules play a crucial role in cellular and humoral
immunity by forming peptide–MHC-II (pMHC-II) complexes. The three-dimensional …
immunity by forming peptide–MHC-II (pMHC-II) complexes. The three-dimensional …
Dynamical insights into the differential characteristics of Mycobacterium avium subsp. paratuberculosis peptide binding to HLA-DRB1 proteins associated with multiple …
Mycobacterium avium subsp. paratuberculosis (MAP) infections have been recently linked to
multiple sclerosis in Sardinian population, with an amino acid sequence 301–309 of …
multiple sclerosis in Sardinian population, with an amino acid sequence 301–309 of …
Antigenic peptide molecular recognition by the DRB1–DQB1 haplotype modulates multiple sclerosis susceptibility
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system that has a
notably high incidence in Sardinia. Our study focuses on two HLA class II haplotypes …
notably high incidence in Sardinia. Our study focuses on two HLA class II haplotypes …
[HTML][HTML] A recombinant multi-epitope peptide vaccine based on MOMP and CPSIT_p6 protein protects against Chlamydia psittaci lung infection
Y Li, K Zheng, Y Tan, Y Wen, C Wang, Q Chen… - Applied Microbiology …, 2019 - Springer
Chlamydia psittaci is an obligate intracellular pathogen with a broad host range that can
lead to severe infectious disease by transferring from birds to humans. Vaccination has been …
lead to severe infectious disease by transferring from birds to humans. Vaccination has been …
[HTML][HTML] Non-Glycosylated SARS-CoV-2 Omicron BA. 5 Receptor Binding Domain (RBD) with a Native-like Conformation Induces a Robust Immune Response with …
R Wongnak, S Brindha, M Oba, T Yoshizue, MD Islam… - Molecules, 2024 - mdpi.com
The Omicron BA. 5 variant of SARS-CoV-2 is known for its high transmissibility and its
capacity to evade immunity provided by vaccine protection against the (original) Wuhan …
capacity to evade immunity provided by vaccine protection against the (original) Wuhan …
[HTML][HTML] In silico analysis and recombinant expression of BamA protein as a universal vaccine against Escherichia coli in mice
Q Guan, X Wang, X Wang, D Teng, J Wang - Applied microbiology and …, 2016 - Springer
Colibacillosis, caused by pathogenic Escherichia coli, is a common disease in animals and
human worldwide with extensive losses in breeding industry and with millions of people …
human worldwide with extensive losses in breeding industry and with millions of people …
Characterization of T cells specific for CFP-10 and ESAT-6 in Mycobacterium tuberculosis-infected Mauritian cynomolgus macaques
A Ellis, A Balgeman, M Rodgers, C Updike… - Infection and …, 2017 - Am Soc Microbiol
Nonhuman primates can be used to study host immune responses to Mycobacterium
tuberculosis. Mauritian cynomolgus macaques (MCMs) are a unique group of animals that …
tuberculosis. Mauritian cynomolgus macaques (MCMs) are a unique group of animals that …