Dynamic regulation of the filamentous actin (F-actin) cytoskeleton is critical to numerous
physical cellular processes, including cell adhesion, migration and division. Each of these …

The cell is a mechanical machine, and continuum mechanics of the fluid cytoplasm and the
viscoelastic deforming cytoskeleton play key roles in cell physiology. We review …

The cytoplasm is the largest part of the cell by volume and hence its rheology sets the rate at
which cellular shape changes can occur. Recent experimental evidence suggests that …

When an indenter is pressed into a gel to a fixed depth, the solvent in the gel migrates, and
the force on the indenter relaxes. Within the theory of poroelasticity, the force relaxation …

Little is known about the complex interplay between the extracellular mechanical
environment and the mechanical properties that characterize the dynamic intracellular …

An elastomeric gel is a mixture of a polymer network and a solvent. In response to changes
in mechanical forces and in the chemical potential of the solvent in the environment, the gel …

Active transport in the cytoplasm plays critical roles in living cell physiology. However, the
mechanical resistance that intracellular compartments experience, which is governed by the …

Nanobiomechanics of living cells is very important to understand cell–materials interactions.
This would potentially help to optimize the surface design of the implanted materials and …

Several computational models based on experimental techniques and theories have been
proposed to describe cytoskeleton (CSK) mechanics. Tensegrity is a prominent model for …

Fibronectin (Fn) forms a fibrillar network that controls cell behavior in both physiological and
diseased conditions including cancer. Indeed, breast cancer-associated stromal cells not …