Nature and nurture: the complex genetics of myopia and refractive error

R Wojciechowski - Clinical genetics, 2011 - Wiley Online Library
Wojciechowski R. Nature and nurture: the complex genetics of myopia and refractive error.
The refractive errors, myopia and hyperopia, are optical defects of the visual system that can …

[HTML][HTML] Gap junction-mediated electrical transmission: regulatory mechanisms and plasticity

AE Pereda, S Curti, G Hoge, R Cachope… - … et Biophysica Acta (BBA …, 2013 - Elsevier
The term synapse applies to cellular specializations that articulate the processing of
information within neural circuits by providing a mechanism for the transfer of information …

A genome-wide association study identifies a susceptibility locus for refractive errors and myopia at 15q14

AM Solouki, VJM Verhoeven, CM Van Duijn… - Nature …, 2010 - nature.com
Refractive errors are the most common ocular disorders worldwide and may lead to
blindness. Although this trait is highly heritable, identification of susceptibility genes has …

Adenosine and dopamine receptors coregulate photoreceptor coupling via gap junction phosphorylation in mouse retina

H Li, Z Zhang, MR Blackburn, SW Wang… - Journal of …, 2013 - Soc Neuroscience
Gap junctions in retinal photoreceptors suppress voltage noise and facilitate input of rod
signals into the cone pathway during mesopic vision. These synapses are highly plastic and …

Double cones and the diverse connectivity of photoreceptors and bipolar cells in an avian retina

A Günther, K Dedek, S Haverkamp, S Irsen… - Journal of …, 2021 - Soc Neuroscience
Double cones are the most common photoreceptor cell type in most avian retinas, but their
precise functions remain a mystery. Among their suggested functions are luminance …

Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium

VJM Verhoeven, PG Hysi, SM Saw, V Vitart, A Mirshahi… - Human genetics, 2012 - Springer
Myopia is a complex genetic disorder and a common cause of visual impairment among
working age adults. Genome-wide association studies have identified susceptibility loci on …

Photoreceptor coupling is controlled by connexin 35 phosphorylation in zebrafish retina

H Li, AZ Chuang, J O'Brien - Journal of Neuroscience, 2009 - Soc Neuroscience
Electrical coupling of neurons is widespread throughout the CNS and is observed among
retinal photoreceptors from essentially all vertebrates. Coupling dampens voltage noise in …

Gap junctional coupling in the vertebrate retina: variations on one theme?

B Völgyi, T Kovács-Öller, T Atlasz, M Wilhelm… - Progress in retinal and …, 2013 - Elsevier
Gap junctions connect cells in the bodies of all multicellular organisms, forming either
homologous or heterologous (ie established between identical or different cell types …

Expression of connexin genes in the human retina

G Söhl, A Joussen, N Kociok, K Willecke - BMC ophthalmology, 2010 - Springer
Background Gap junction channels allow direct metabolically and electrical coupling
between adjacent cells in various mammalian tissues. Each channel is composed of 12 …

Update on the epidemiology and genetics of myopic refractive error

JC Sherwin, DA Mackey - Expert Review of Ophthalmology, 2013 - Taylor & Francis
While myopia is an increasingly common refractive error worldwide, its prevalence is
greatest in urbanized regions in east Asia. Myopia is a complex multifactorial ocular disorder …