Nature and nurture: the complex genetics of myopia and refractive error
R Wojciechowski - Clinical genetics, 2011 - Wiley Online Library
Wojciechowski R. Nature and nurture: the complex genetics of myopia and refractive error.
The refractive errors, myopia and hyperopia, are optical defects of the visual system that can …
The refractive errors, myopia and hyperopia, are optical defects of the visual system that can …
[HTML][HTML] Gap junction-mediated electrical transmission: regulatory mechanisms and plasticity
The term synapse applies to cellular specializations that articulate the processing of
information within neural circuits by providing a mechanism for the transfer of information …
information within neural circuits by providing a mechanism for the transfer of information …
A genome-wide association study identifies a susceptibility locus for refractive errors and myopia at 15q14
AM Solouki, VJM Verhoeven, CM Van Duijn… - Nature …, 2010 - nature.com
Refractive errors are the most common ocular disorders worldwide and may lead to
blindness. Although this trait is highly heritable, identification of susceptibility genes has …
blindness. Although this trait is highly heritable, identification of susceptibility genes has …
Adenosine and dopamine receptors coregulate photoreceptor coupling via gap junction phosphorylation in mouse retina
H Li, Z Zhang, MR Blackburn, SW Wang… - Journal of …, 2013 - Soc Neuroscience
Gap junctions in retinal photoreceptors suppress voltage noise and facilitate input of rod
signals into the cone pathway during mesopic vision. These synapses are highly plastic and …
signals into the cone pathway during mesopic vision. These synapses are highly plastic and …
Double cones and the diverse connectivity of photoreceptors and bipolar cells in an avian retina
Double cones are the most common photoreceptor cell type in most avian retinas, but their
precise functions remain a mystery. Among their suggested functions are luminance …
precise functions remain a mystery. Among their suggested functions are luminance …
Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium
VJM Verhoeven, PG Hysi, SM Saw, V Vitart, A Mirshahi… - Human genetics, 2012 - Springer
Myopia is a complex genetic disorder and a common cause of visual impairment among
working age adults. Genome-wide association studies have identified susceptibility loci on …
working age adults. Genome-wide association studies have identified susceptibility loci on …
Photoreceptor coupling is controlled by connexin 35 phosphorylation in zebrafish retina
H Li, AZ Chuang, J O'Brien - Journal of Neuroscience, 2009 - Soc Neuroscience
Electrical coupling of neurons is widespread throughout the CNS and is observed among
retinal photoreceptors from essentially all vertebrates. Coupling dampens voltage noise in …
retinal photoreceptors from essentially all vertebrates. Coupling dampens voltage noise in …
Gap junctional coupling in the vertebrate retina: variations on one theme?
Gap junctions connect cells in the bodies of all multicellular organisms, forming either
homologous or heterologous (ie established between identical or different cell types …
homologous or heterologous (ie established between identical or different cell types …
Expression of connexin genes in the human retina
G Söhl, A Joussen, N Kociok, K Willecke - BMC ophthalmology, 2010 - Springer
Background Gap junction channels allow direct metabolically and electrical coupling
between adjacent cells in various mammalian tissues. Each channel is composed of 12 …
between adjacent cells in various mammalian tissues. Each channel is composed of 12 …
Update on the epidemiology and genetics of myopic refractive error
JC Sherwin, DA Mackey - Expert Review of Ophthalmology, 2013 - Taylor & Francis
While myopia is an increasingly common refractive error worldwide, its prevalence is
greatest in urbanized regions in east Asia. Myopia is a complex multifactorial ocular disorder …
greatest in urbanized regions in east Asia. Myopia is a complex multifactorial ocular disorder …