Molecular targets of atypical antipsychotics: From mechanism of action to clinical differences

S Aringhieri, M Carli, S Kolachalam, V Verdesca… - Pharmacology & …, 2018 - Elsevier
The introduction of atypical antipsychotics (AAPs) since the discovery of its prototypical drug
clozapine has been a revolutionary pharmacological step for treating psychotic patients as …

Cannabidiol as a promising strategy to treat and prevent movement disorders?

FF Peres, AC Lima, JEC Hallak, JA Crippa… - Frontiers in …, 2018 - frontiersin.org
Movement disorders such as Parkinson's disease and dyskinesia are highly debilitating
conditions linked to oxidative stress and neurodegeneration. When available, the …

Deutetrabenazine for treatment of involuntary movements in patients with tardive dyskinesia (AIM-TD): a double-blind, randomised, placebo-controlled, phase 3 trial

KE Anderson, D Stamler, MD Davis, SA Factor… - The Lancet …, 2017 - thelancet.com
Background Tardive dyskinesia results from exposure to dopamine receptor antagonists,
such as typical and atypical antipsychotics. If clinically appropriate, clinicians often manage …

Medication-induced tardive dyskinesia: a review and update

EM Cornett, M Novitch, AD Kaye, V Kata… - Ochsner …, 2017 - ochsnerjournal.org
Background: Tardive dyskinesia (TD) is a movement disorder that causes involuntary,
repetitive body movements and is commonly seen in patients who are on long-term …

Tardive syndromes

D Savitt, J Jankovic - Journal of the neurological sciences, 2018 - Elsevier
Tardive syndromes are a group of hyperkinetic and hypokinetic movement disorders that
occur after some delay following exposure to dopamine receptor blocking agents such as …

Pathophysiology, prognosis and treatment of tardive dyskinesia

H Takeuchi, Y Mori, Y Tsutsumi - Therapeutic advances in …, 2022 - journals.sagepub.com
Tardive dyskinesia (TD), a movement disorder associated with antipsychotics, most
frequently affects the lower face and jaw muscles, but can also affect walking, breathing and …

Protracted withdrawal syndrome after stopping antidepressants: a descriptive quantitative analysis of consumer narratives from a large internet forum

MP Hengartner, L Schulthess… - Therapeutic …, 2020 - journals.sagepub.com
Background: Protracted withdrawal syndrome (PWS) after stopping antidepressants
(frequently also referred to as post-acute withdrawal syndrome or PAWS) has been …

Traditional uses, chemical compounds, pharmacological activities and clinical studies on the traditional Chinese prescription Yi-Gan San

SY Yang, ZX Lin, YF Xian, HM Zhang, HX Xu - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance A widely used traditional prescription, Yi-Gan San (YGS) is
a remedy for neurodegenerative disorders. The formulation consists of seven Chinese …

Effect of tardive dyskinesia on quality of life in patients with bipolar disorder, major depressive disorder, and schizophrenia

J McEvoy, SK Gandhi, AA Rizio, S Maher… - Quality of Life …, 2019 - Springer
Purpose Tardive dyskinesia (TD) is a common but serious hyperkinetic movement disorder
and side effect of antipsychotic medications used to treat bipolar disorder (BD), major …

Cannabidiol prevents motor and cognitive impairments induced by reserpine in rats

FF Peres, R Levin, MA Suiama, MC Diana… - Frontiers in …, 2016 - frontiersin.org
Cannabidiol (CBD) is a non-psychotomimetic compound from Cannabis sativa that presents
antipsychotic, anxiolytic, anti-inflammatory, and neuroprotective effects. In Parkinson's …