The Raman spectrum of living cells and microorganisms contains highly specific fingerprint‐
like signatures, useful in unequivocally identifying different species and interpreting …

Direct imaging of metabolism in cells or multicellular organisms is important for
understanding many biological processes. Raman scattering (RS) microscopy, particularly …

Neurosurgeons often treat patients with conditions in which time is of the essence and
delaying surgery may negatively affect outcome. We have halted all elective cases, but will …

Raman microspectroscopy is an emerging analytical tool that can monitor the biochemical
composition of biological or biomedical specimens, including proteins, cells, and tissues, as …

This article shows the latest advances in the spectroscopic analysis of cancer cells to identify
pathological changes and understand the mechanism of metastasis using stimulated …

Background Intraoperative pathologic diagnosis traditionally involves frozen section
histopathology, which may be labor and time intensive. Indeed, a technique that streamlines …

Surgical pathology workflow involves multiple labor-intensive steps, such as tissue removal,
fixation, embedding, sectioning, staining, and microscopic examination. This process is time …

Intraoperative histopathological examinations are routinely performed to provide
neurosurgeons with information about the entity of tumor tissue. Here, we quantified the …

Histopathological diagnosis is the current standard for the classification of brain and spine
tumors. Raman spectroscopy has been reported to allow fast and easy intraoperative tissue …

Introduction The intrinsic autofluorescence of biological tissues interferes with the detection
of fluorophores administered for fluorescence guidance, an emerging auxiliary technique in …