Exposure to stress during critical periods in development can have severe long-term
consequences, increasing overall risk on psychopathology. One of the key stress response …

Folate deficiency in the periconceptional period contributes to neural tube defects; deficits in
vitamin B12 (cobalamin) have negative consequences on the developing brain during …

Stress has long been associated with the development of neuropsychiatric and neurological
disorders. The effects of stress vary depending upon the age during which the stress is …

We sought to extend earlier work by examining whether there are ordinary variations in
human maternal caregiving behavior (MCB) that are related to stress reactivity in infants. We …

A number of lines of converging evidence suggest that brain-derived neurotrophic factor
(BDNF) may play a role in the onset and treatment of bipolar disorder. We review pertinent …

Early life stress (ELS) is implicated in the etiology of multiple psychiatric disorders. Important
biological effects of ELS are manifested in stress-susceptible regions of the hippocampus …

Early life stress in humans can affect the development of neurons and neurotransmitter
systems and predispose an individual to the subsequent development of depression …

Children that are abused have an increased risk for developing psychiatric disorders later in
life, because of the negative effects of stress on the developing brain. We used a maternal …

Early life experiences can affect brain development, contributing to shape interindividual
differences in stress vulnerability and anxiety-like behavior. In rodents, high levels of …

The present study was aimed to evaluate the behavioral and molecular effects of maternal
deprivation in adult rats. To this aim, male rats deprived and non-deprived were assessed in …