Two major mechanisms are involved in the formation of blood vasculature: vasculogenesis
and angiogenesis. The former term describes the formation of a capillary-like network from …

In the developing embryo, tissues differentiate, deform, and move in an orchestrated manner
to generate various biological shapes driven by the complex interplay between genetic …

Despite major scientific, medical and technological advances over the last few decades, a
cure for cancer remains elusive. The disease initiation is complex, and including initiation …

Blood vessels form either when dispersed endothelial cells (the cells lining the inner walls of
fully formed blood vessels) organize into a vessel network (vasculogenesis), or by sprouting …

Tumour growth is a multifactorial process, which has stimulated in recent decades the
development of numerous models trying to figure out the mechanisms controlling solid …

Considering their extremely complicated and hierarchical structure, a long standing question
in vascular physio-pathology is how to characterize blood vessels patterns, including which …

Most studies of pattern formation place particular emphasis on its role in the development of
complex multicellular body plans. In simpler organisms, however, pattern formation is …

The extracellular matrix (ECM) is a highly complex structure through which biochemical and
mechanical signals are transmitted. In processes of cell migration, the ECM also acts as a …

Over the last 30 years, numerous research groups have attempted to provide mathematical
descriptions of the skin wound healing process. The development of theoretical models of …

Tumor angiogenesis is the process by which new blood vessels are formed and enhance
the oxygenation and growth of tumors. As angiogenesis is recognized as being a critical …