Lipid-based nanoparticle technologies for liver targeting

R Böttger, G Pauli, PH Chao, NAL Fayez… - Advanced drug delivery …, 2020 - Elsevier
Liver diseases such as hepatitis, cirrhosis, and hepatocellular carcinoma are global health
problems accounting for approximately 800 million cases and over 2 million deaths per year …

Lactosylated Chitosan Nanoparticles Potentiate the Anticancer Effects of Telmisartan In Vitro and in a N-Nitrosodiethylamine-Induced Mice Model of Hepatocellular …

M Nasr, AY Kira, S Saber, EA Essa… - Molecular …, 2023 - ACS Publications
Hepatocellular carcinoma (HCC) is the leading cause of cancer-related mortality worldwide.
Telmisartan (TLM), a BSC class II drug, has been reported to have antiproliferative activity in …

Polymer drug conjugates: recent advancements in various diseases

J Singh, S Desai, S Yadav… - Current …, 2016 - ingentaconnect.com
During the past decade, the arena of polymer therapeutics has acquired considerable
interest and accompanied by advanced designs and chemical properties of polymer-drug …

Telmisartan-Loaded Lactosylated Chitosan Nanoparticles as a Liver Specific Delivery System: Synthesis, Optimization and Targeting Efficiency

M Nasr, AY Kira, S Saber, EA Essa, SA El-Gizawy - AAPS PharmSciTech, 2023 - Springer
Hepatocellular carcinoma (HCC) has a significant economic impact and a high mortality
rate. Telmisartan (TLM) is a potential therapy for HCC, but it has a limited scope in drug …

Comparison between two different click strategies to synthesize fluorescent nanogels for therapeutic applications

E Mauri, I Moroni, L Magagnin, M Masi… - Reactive and Functional …, 2016 - Elsevier
The development of nanogels as nanoscale multifunctional polymer-based matrices for
controlled drug and gene delivery purposes has been the subject of intense research during …

Tumor-Targeting Polymer–Drug Conjugate for Liver Cancer Treatment In Vitro

J Xu, S Lin, H Hu, Q Xing, J Geng - Polymers, 2022 - mdpi.com
Bufalin (buf) has poor solubility in aqueous solution, poor tumor targeting, and many non-
specific toxic and side effects. The advantages of high-molecular-weight polymer conjugates …

[HTML][HTML] Controlling drug release from non-aqueous environments: Moderating delivery from ocular silicone oil drug reservoirs to combat proliferative vitreoretinopathy

H Cauldbeck, M Le Hellaye, M Long… - Journal of Controlled …, 2016 - Elsevier
In a number of cases of retinal detachment, treatment may require the removal of the
vitreous humour within the eye and replacement with silicone oil to aid healing of the retina …

[PDF][PDF] The emerging role of lipid nanosystems and nanomicelles in liver diseases.

S Jacob, AB Nair, SHS Boddu… - European Review for …, 2023 - europeanreview.org
Nanoparticles (NPs) exhibit remarkable potential in the diagnosis and treatment of various
liver ailments, including primary liver cancer or hepatocellular carcinoma (HCC), liver …

Interaction of Curcumin with Poly Lactic-Co-Glycolic Acid and Poly Diallyldimethylammonium Chloride By Fluorescence Spectroscopy

H Zakaria, R El Kurdi, D Patra - Journal of Fluorescence, 2022 - Springer
Abstract Poly Lactic-Co-Glycolic Acid (PLGA) and Poly Diallyldimethylammonium Chloride
(PDDA) are widely being used for drug delivery and curcumin is being studied as potential …

Maleimidation of dextran and the application in designing a dextran–camptothecin conjugate

Q Zhu, B Bao, Q Zhang, J Yu, W Lu - RSC advances, 2018 - pubs.rsc.org
Camptothecin analogs, as commonly used chemotherapy drugs, usually have poor water
solubility which has limited their use in the clinic. In order to improve the water-solubility of …