[HTML][HTML] Applications of proteomics in ovarian cancer: dawn of a new era
A Ghose, SVN Gullapalli, N Chohan, A Bolina… - Proteomes, 2022 - mdpi.com
The ability to identify ovarian cancer (OC) at its earliest stages remains a challenge. The
patients present an advanced stage at diagnosis. This heterogeneous disease has …
patients present an advanced stage at diagnosis. This heterogeneous disease has …
[HTML][HTML] Molecular, cellular and systemic aspects of epithelial ovarian cancer and its tumor microenvironment
E Schoutrop, L Moyano-Galceran, S Lheureux… - Seminars in cancer …, 2022 - Elsevier
Ovarian cancer encompasses a heterogeneous group of malignancies that involve the
ovaries, fallopian tubes and the peritoneal cavity. Despite major advances made within the …
ovaries, fallopian tubes and the peritoneal cavity. Despite major advances made within the …
[HTML][HTML] PI3K-AKT-mTOR and NFκB pathways in ovarian cancer: implications for targeted therapeutics
Ovarian cancer is the most lethal gynecologic malignancy in the United States, with an
estimated 22,530 new cases and 13,980 deaths in 2019. Recent studies have indicated that …
estimated 22,530 new cases and 13,980 deaths in 2019. Recent studies have indicated that …
Mitochondrial fission causes cisplatin resistance under hypoxic conditions via ROS in ovarian cancer cells
Mitochondria undergo fission and fusion continually for survival through the course of
cellular adaption processes in response to changes in the surrounding environment …
cellular adaption processes in response to changes in the surrounding environment …
[HTML][HTML] Glycoproteomics-based signatures for tumor subtyping and clinical outcome prediction of high-grade serous ovarian cancer
Inter-tumor heterogeneity is a result of genomic, transcriptional, translational, and post-
translational molecular features. To investigate the roles of protein glycosylation in the …
translational molecular features. To investigate the roles of protein glycosylation in the …
Single-cell dissection of the multiomic landscape of high-grade serous ovarian cancer
Y Wang, H Xie, X Chang, W Hu, M Li, Y Li, H Liu… - Cancer Research, 2022 - AACR
High-grade serous cancer (HGSC) is the most common subtype of ovarian cancer. HGSC is
highly aggressive with poor patient outcomes, and a deeper understanding of HGSC …
highly aggressive with poor patient outcomes, and a deeper understanding of HGSC …
[HTML][HTML] Genetic heterogeneity and evolutionary history of high-grade ovarian carcinoma and matched distant metastases
Background High-grade serous ovarian carcinoma (HGSOC) is the most frequent type of
ovarian carcinoma, associated with poor clinical outcome and metastatic disease. Although …
ovarian carcinoma, associated with poor clinical outcome and metastatic disease. Although …
[HTML][HTML] Chloroquine reverses chemoresistance via upregulation of p21WAF1/CIP1 and autophagy inhibition in ovarian cancer
JR Hwang, WY Kim, YJ Cho, JY Ryu, JJ Choi… - Cell death & …, 2020 - nature.com
Overcoming drug-resistance is a big challenge to improve the survival of patients with
epithelial ovarian cancer (EOC). In this study, we investigated the effect of chloroquine (CQ) …
epithelial ovarian cancer (EOC). In this study, we investigated the effect of chloroquine (CQ) …
[HTML][HTML] An overview of ovarian cancer: the role of cancer stem cells in chemoresistance and a precision medicine approach targeting the Wnt pathway with the …
Simple Summary Ovarian cancer is one of the deadliest cancers in women and is
unfortunately detected only in its later stages, by which time it will have metastasized to …
unfortunately detected only in its later stages, by which time it will have metastasized to …
Sodium molybdate inhibits the growth of ovarian cancer cells via inducing both ferroptosis and apoptosis
G Mao, D Xin, Q Wang, D Lai - Free Radical Biology and Medicine, 2022 - Elsevier
Ovarian cancer has the most mortality of all gynecologic malignancies. High-grade serous
ovarian carcinoma (HGSOC) is the most common and deadly type of ovarian cancer. Tumor …
ovarian carcinoma (HGSOC) is the most common and deadly type of ovarian cancer. Tumor …