The ability to identify ovarian cancer (OC) at its earliest stages remains a challenge. The
patients present an advanced stage at diagnosis. This heterogeneous disease has …

Ovarian cancer encompasses a heterogeneous group of malignancies that involve the
ovaries, fallopian tubes and the peritoneal cavity. Despite major advances made within the …

Ovarian cancer is the most lethal gynecologic malignancy in the United States, with an
estimated 22,530 new cases and 13,980 deaths in 2019. Recent studies have indicated that …

Mitochondria undergo fission and fusion continually for survival through the course of
cellular adaption processes in response to changes in the surrounding environment …

Inter-tumor heterogeneity is a result of genomic, transcriptional, translational, and post-
translational molecular features. To investigate the roles of protein glycosylation in the …

High-grade serous cancer (HGSC) is the most common subtype of ovarian cancer. HGSC is
highly aggressive with poor patient outcomes, and a deeper understanding of HGSC …

Background High-grade serous ovarian carcinoma (HGSOC) is the most frequent type of
ovarian carcinoma, associated with poor clinical outcome and metastatic disease. Although …

Overcoming drug-resistance is a big challenge to improve the survival of patients with
epithelial ovarian cancer (EOC). In this study, we investigated the effect of chloroquine (CQ) …

Simple Summary Ovarian cancer is one of the deadliest cancers in women and is
unfortunately detected only in its later stages, by which time it will have metastasized to …

Ovarian cancer has the most mortality of all gynecologic malignancies. High-grade serous
ovarian carcinoma (HGSOC) is the most common and deadly type of ovarian cancer. Tumor …