How to ventilate obstructive and asthmatic patients

A Demoule, L Brochard, M Dres, L Heunks… - Intensive care …, 2020 - Springer
Exacerbations are part of the natural history of chronic obstructive pulmonary disease and
asthma. Severe exacerbations can cause acute respiratory failure, which may ultimately …

[HTML][HTML] Mechanical cardiopulmonary interactions during exercise in health and disease

WS Cheyne, MI Harper, JC Gelinas… - Journal of Applied …, 2020 - journals.physiology.org
The heart and lungs are anatomically coupled through the pulmonary circulation and coexist
within the sealed thoracic cavity, making the function of these systems highly …

Impaired central hemodynamics in chronic obstructive pulmonary disease during submaximal exercise

JR Smith, BD Johnson… - Journal of applied …, 2019 - journals.physiology.org
It is unknown whether central hemodynamics are impaired during exercise in chronic
obstructive pulmonary disease (COPD) patients. We hypothesized that, at a similar absolute …

Left ventricular volume and wall stress are linked to lung function impairment in COPD

P Alter, RA Jörres, H Watz, T Welte, S Gläser… - International journal of …, 2018 - Elsevier
Background Cardiovascular comorbidities are common in chronic obstructive pulmonary
disease (COPD). We examined the association between airflow limitation, hyperinflation and …

Hemodynamic effects of incremental lung hyperinflation

WS Cheyne, JC Gelinas… - American Journal of …, 2018 - journals.physiology.org
Dynamic hyperinflation (DH) is common in chronic obstructive pulmonary disease and is
associated with dyspnea and exercise intolerance. DH also has adverse cardiac effects …

Blood shifts between body compartments during submaximal exercise with induced expiratory flow limitation in healthy humans

F Stucky, B Uva, B Kayser… - The Journal of …, 2023 - Wiley Online Library
External expiratory flow limitation (EFLe) can be applied in healthy subjects to mimic the
effects of chronic obstructive pulmonary disease during exercise. At maximal exercise …

Cardio-respiratory interactions in acute asthma

M Caplan, O Hamzaoui - Frontiers in Physiology, 2023 - frontiersin.org
Asthma encompasses of respiratory symptoms that occur intermittently and with varying
intensity accompanied by reversible expiratory airflow limitation. In acute exacerbations, it …

A history of asthma from childhood and left ventricular mass in asymptomatic young adults: the Bogalusa Heart Study

D Sun, T Wang, Y Heianza, J Lv, L Han, F Rabito… - JACC: Heart Failure, 2017 - jacc.org
Objectives: This study aimed to examine whether a history of asthma from childhood is
associated with left ventricular (LV) mass in adulthood. Background: Asthma has been …

Cardiorespiratory coupling is associated with exercise capacity in patients with chronic obstructive pulmonary disease

YC Huang, TY Lin, HT Wu, PJ Chang, CY Lo… - BMC Pulmonary …, 2021 - Springer
Background The interaction between the pulmonary function and cardiovascular mechanics
is a crucial issue, particularly when treating patients with chronic obstructive pulmonary …

The haemodynamic response to incremental increases in negative intrathoracic pressure in healthy humans

WS Cheyne, JC Gelinas, ND Eves - Experimental physiology, 2018 - Wiley Online Library
New Findings What is the central question of this study? The haemodynamic response to
incremental increases in negative intrathoracic pressure (nITP) during spontaneous …