A review on analytical strategies for the assessment of recently approved direct acting antiviral drugs
Human beings are in dire need of developing an efficient treatment against fierce viruses
like hepatitis C virus (HCV) and Coronavirus (COVID-19). These viruses have already …
like hepatitis C virus (HCV) and Coronavirus (COVID-19). These viruses have already …
Computational design for eco-friendly visible spectrophotometric platform used for the assay of the antiviral agent in pharmaceutical dosage form
A Elsonbaty, AW Madkour, AM Abdel-Raoof… - … Acta Part A: Molecular …, 2022 - Elsevier
Nowadays, the analytical community is focusing on developing new analytical methods that
incorporate principles of green analytical chemistry to reduce adverse impacts on the …
incorporate principles of green analytical chemistry to reduce adverse impacts on the …
Optimization and modeling of a green dual detected RP-HPLC method by UV and fluorescence detectors using two level full factorial design for simultaneous …
HI EL-Shorbagy, F Elsebaei, SF Hammad… - Microchemical …, 2019 - Elsevier
A simple, rapid, selective, linear, precise, accurate and eco-friendly RP-HPLC-UV-
Fluorescence method was developed by 2 3 full factorial design and validated for …
Fluorescence method was developed by 2 3 full factorial design and validated for …
ε-MnO2-modified graphite electrode as a novel electrochemical sensor for the ultrasensitive detection of the newly FDA approved Hepatitis C antiviral drug ledipasvir
A novel, simple and sensitive electrochemical method for the determination of ledipasvir
(LED), the newly FDA approved Hepatitis C antiviral drug was developed and validated …
(LED), the newly FDA approved Hepatitis C antiviral drug was developed and validated …
Electroanalytical investigation and determination of hepatitis C antiviral drug ledipasvir at a non-modified boron-doped diamond electrode
This study is about the use of the boron-doped diamond electrode pretreated
electrochemically (anodic and subsequent cathodic) in the voltammetric determination of …
electrochemically (anodic and subsequent cathodic) in the voltammetric determination of …
Eco friendly stability indicating HPTLC method for simultaneous determination of sofosbuvir and ledipasvir in pharmaceutical tablets and HPTLC-MS characterization …
AA El-Waey, RA Abdel-Salam, GM Hadad… - Microchemical …, 2023 - Elsevier
Recently, the analytical community has shown increasing interest in developing more
environment-friendly practices by eliminating or reducing the use of hazardous chemicals …
environment-friendly practices by eliminating or reducing the use of hazardous chemicals …
Recent advances in the chromatographic determination of the most commonly used anti‐hepatitis C drug sofosbuvir and its co‐administered drugs in human plasma
MAH Abdel‐Tawab, MG Abd El‐Moghny… - Biomedical …, 2022 - Wiley Online Library
Sofosbuvir is a direct‐acting antiviral drug that inhibits hepatitis C virus (HCV) NS5B
polymerase, which in turn affects the virus replication inside biological systems. The clinical …
polymerase, which in turn affects the virus replication inside biological systems. The clinical …
A new fluorescence probe for sofosbuvir analysis in dosage form and spiked human plasma
A simple, rapid, and low‐cost technique was developed to allow reliable analysis of the anti‐
hepatitis C drug sofosbuvir in bulk, tablet form, and spiked human plasma. This method …
hepatitis C drug sofosbuvir in bulk, tablet form, and spiked human plasma. This method …
Validated 1H and 19F nuclear magnetic resonance for the quantitative determination of the hepatitis C antiviral drugs sofosbuvir, ledipasvir, and daclatasvir in tablet …
Use of quantitative NMR (qNMR) is increasing nowadays for the determination of active
pharmaceutical drugs in their bulk drug raw materials and in pharmaceutical formulations. In …
pharmaceutical drugs in their bulk drug raw materials and in pharmaceutical formulations. In …
Micelle sensitized synchronous spectrofluorimetric approaches for the simultaneous determination of simeprevir and ledipasvir: Application to pharmaceutical …
Simeprevir (SMV) is commonly co-administered with ledipasvir (LDS) and sofosbuvir (SOF)
as an effective combination regimen for treatment naive hepatitis C virus infected patients. In …
as an effective combination regimen for treatment naive hepatitis C virus infected patients. In …