Towards the elimination of visceral leishmaniasis as a public health problem in east Africa: reflections on an enhanced control strategy and a call for action

J Alvar, M den Boer, DA Dagne - The Lancet Global Health, 2021 - thelancet.com
East Africa is the world region most affected by visceral leishmaniasis, accounting for 45% of
cases globally that were reported to WHO in 2018, with an annual incidence that is only …

Host-directed drug therapies for neglected tropical diseases caused by protozoan parasites

S Varikuti, BK Jha, G Volpedo, NM Ryan… - Frontiers in …, 2018 - frontiersin.org
The neglected tropical diseases (NTDs) caused by protozoan parasites are responsible for
significant morbidity and mortality worldwide. Current treatments using anti-parasitic drugs …

Effective drug combination for Caenorhabditis elegans nematodes discovered by output-driven feedback system control technique

X Ding, Z Njus, T Kong, W Su, CM Ho, S Pandey - Science advances, 2017 - science.org
Infections from parasitic nematodes (or roundworms) contribute to a significant disease
burden and productivity losses for humans and livestock. The limited number of …

Global research on cysticercosis and neurocysticercosis: A bibliometric analysis

G Gonzalez-Alcaide, N Sosa, L Shevy… - Frontiers in Veterinary …, 2023 - frontiersin.org
Background Cysticercosis is a parasitic infection caused by the larval stage Taenia solium.
As a neglected tropical disease that is also difficult to diagnose, cysticercosis constitutes an …

Multiplex PCR for bacterial, viral and protozoal pathogens in persistent diarrhoea or persistent abdominal pain in Côte d'Ivoire, Mali and Nepal

JK Jasuja, F Bub, J Veit, HKM Fofana, M Sacko… - Scientific Reports, 2024 - nature.com
In contrast to acute diarrhoea, the aetiology of persistent digestive disorders (≥ 14 days) is
poorly understood in low-resource settings and conventional diagnostic approaches lack …

Leishmaniasis: Current Trends in Microbiology and Pharmacology

I Adams, AA Kwapong, E Boafo, E Twum… - Rising Contagious …, 2024 - Wiley Online Library
Leishmaniasis is a neglected tropical disease infecting the world's poorest populations in
over 90 countries throughout Asia, Africa, the Middle East, and Central and South America …

[HTML][HTML] Clinical spectrum, etiology, and outcome of neurological disorders in the rural hospital of Mosango, the Democratic Republic of Congo

D Mukendi, JRL Kalo, A Mpanya… - The American journal …, 2017 - ncbi.nlm.nih.gov
There is little published information on the epidemiology of neurological disorders in rural
Central Africa, although the burden is considered to be substantial. This study aimed to …

Persistent febrile illnesses in Nepal: A systematic review

KD Koirala, F Chappuis, K Verdonck… - Indian Journal of …, 2018 - journals.lww.com
Methods: In this study, a review of the potential causes of persistent fever defined as fever of
more than seven days was done in Nepal, with a focus on nine pathogen-specific …

Where there is no brain imaging: safety and diagnostic value of lumbar puncture in patients with neurological disorders in a rural hospital of Central Africa

D Mukendi, JRL Kalo, T Kayembe, P Lutumba… - Journal of the …, 2018 - Elsevier
Abstract Analysis of cerebrospinal fluid (CSF) obtained by lumbar puncture (LP) is an
essential step for the diagnostic approach of neurological disorders, in particular neuro …

PCR-based verification of positive rapid diagnostic tests for intestinal protozoa infections with variable test band intensity

SL Becker, I Müller, P Mertens, M Herrmann, L Zondie… - Acta tropica, 2017 - Elsevier
Stool-based rapid diagnostic tests (RDTs) for pathogenic intestinal protozoa (eg
Cryptosporidium spp. and Giardia intestinalis) allow for prompt diagnosis and treatment in …