CRISPR Cpf1 proteins: structure, function and implications for genome editing
F Safari, K Zare, M Negahdaripour… - Cell & bioscience, 2019 - Springer
CRISPR and CRISPR-associated (Cas) protein, as components of microbial adaptive
immune system, allows biologists to edit genomic DNA in a precise and specific way …
immune system, allows biologists to edit genomic DNA in a precise and specific way …
In vivo delivery of CRISPR-Cas9 genome editing components for therapeutic applications
Since its mechanism discovery in 2012 and the first application for mammalian genome
editing in 2013, CRISPR-Cas9 has revolutionized the genome engineering field and created …
editing in 2013, CRISPR-Cas9 has revolutionized the genome engineering field and created …
CRISPR systems: Novel approaches for detection and combating COVID-19
Abstract Type V and VI CRISPR enzymes are RNA-guided, DNA and RNA-targeting
effectors that allow specific gene knockdown. Cas12 and Cas13 are CRISPR proteins that …
effectors that allow specific gene knockdown. Cas12 and Cas13 are CRISPR proteins that …
Human germline genome editing
R A. Lea, K K. Niakan - Nature Cell Biology, 2019 - nature.com
With the advent of efficient, easy-to-use genome editing by CRISPR–Cas9, editing human
embryos is now possible, providing tremendous opportunities to study gene function and …
embryos is now possible, providing tremendous opportunities to study gene function and …
The interaction of phages and bacteria: the co-evolutionary arms race
Since the dawn of life, bacteria and phages are locked in a constant battle and both are
perpetually changing their tactics to overcome each other. Bacteria use various strategies to …
perpetually changing their tactics to overcome each other. Bacteria use various strategies to …
CRISPR/Cas9 system: a reliable and facile genome editing tool in modern biology
Genome engineering has always been a versatile technique in biological research and
medicine, with several applications. In the last several years, the discovery of Clustered …
medicine, with several applications. In the last several years, the discovery of Clustered …
[HTML][HTML] Knockout of caspase-7 gene improves the expression of recombinant protein in CHO cell line through the cell cycle arrest in G2/M phase
Resumen SAFARI, Fatemeh y AKBARI, Bahman. Knockout of caspase-7 gene improves the
expression of recombinant protein in CHO cell line through the cell cycle arrest in G2/M …
expression of recombinant protein in CHO cell line through the cell cycle arrest in G2/M …
Immunotherapy and CRISPR cas systems: potential cure of COVID-19?
X He, XX Zeng - Drug Design, Development and Therapy, 2023 - Taylor & Francis
The COVID-19 has plunged the world into a pandemic that affected millions. The continually
emerging new variants of concern raise the question as to whether the existing vaccines will …
emerging new variants of concern raise the question as to whether the existing vaccines will …
[HTML][HTML] Caspase-7 deficiency in Chinese hamster ovary cells reduces cell proliferation and viability
SAFARI, Fatemeh et al. Caspase-7 deficiency in Chinese hamster ovary cells reduces cell
proliferation and viability. Biol. Res.[online]. 2020, vol. 53, 52. Epub 19-Nov-2020. ISSN …
proliferation and viability. Biol. Res.[online]. 2020, vol. 53, 52. Epub 19-Nov-2020. ISSN …
Omics and CRISPR in CHO bioproduction: a state-of-the-art review
S Sorourian, A Behzad Behbahani… - Biotechnology and …, 2024 - Springer
Chinese hamster ovary (CHO) cells have been routinely used as a factory for recombinant
proteins for several years, and their improvements have been the focus of consideration …
proteins for several years, and their improvements have been the focus of consideration …